Chewable Tanning Pastille for Oral Mucosa Absorption
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Solution Overview
Problem
Existing orally ingestible tanning compositions face challenges in efficiently delivering skin color-promoting agents due to acidic stomach conditions and inefficient absorption, leading to suboptimal tanning effects.
Innovation Solution
A chewable pastille formulation comprising a gelling agent, sugar, and skin color-promoting agents that are absorbed through the oral mucosa, avoiding stomach acidity and enhancing absorption efficiency.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional tablets or capsules are used for oral administration, then the composition can be easily manufactured and administered, but the active ingredients are exposed to acidic stomach conditions and have inefficient absorption
Solution Approach 1:
The invention extracts the active ingredients from the conventional tablet/capsule delivery system and delivers them directly to the absorption site (oral mucosa) without passing through the harmful stomach environment. This is achieved by using a lozenge formulation that dissolves in the mouth, allowing sublingual or buccal absorption of the active ingredients, thereby taking them out of the harmful gastric pathway.
Solution Approach 2:
The lozenge base acts as an intermediary vehicle that carries the active ingredients from the point of administration (mouth) directly to the absorption site (oral mucosa). This intermediary delivery system bypasses the stomach acidity problem by using the oral cavity as a alternative absorption route, mediating between the administered composition and the bloodstream without exposure to harmful gastric conditions.
2Productivity
If conventional tablets are used, then manufacturing is simple, but the tanning effect is suboptimal due to poor absorption
Solution Approach 1:
The lozenge formulation serves as an intermediary delivery system that enhances absorption efficiency by directing active ingredients to the oral mucosa, a highly vascularized tissue that enables rapid entry into the bloodstream. This intermediary approach bypasses the inefficient gastrointestinal absorption pathway, thereby improving productivity in terms of tanning effect efficiency while maintaining manufacturing simplicity.
3Reliability
If the composition is formulated as a chewable pastille with gelling agent and sugar, then absorption through oral mucosa is enabled, but the formulation complexity increases
Solution Approach 1:
The invention changes the physical and chemical parameters of the formulation by incorporating a gelling agent and sugar to create a chewable pastille matrix. This parameter change transforms the delivery system from a simple tablet to a controlled-dissolution lozenge that maintains active ingredients in contact with the oral mucosa, thereby enabling efficient absorption despite increased formulation complexity.
Solution Approach 2:
The lozenge formulation uses composite materials combining a gelling agent, sugar, and active ingredients to create a matrix that provides both structural integrity and controlled dissolution properties. This composite structure allows the pastille to be chewable and dissolvable in the mouth while maintaining the stability and efficacy of the active ingredients, achieving efficient absorption through oral mucosa.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The chewable pastille formulation achieves rapid and effective skin coloring by allowing active ingredients to be absorbed through the oral mucosa, providing a healthier and more efficient tanning effect compared to conventional tablets.
Implementation Method 1
skin color-promoting agents that are absorbed through the oral mucosa, avoiding stomach acidity and enhancing absorption efficiency
Data Source
AI summary
The invention provides a tanning composition for oral administration by humans, the composition being a chewable pastille comprising:(i) a chewable base comprising a gelling agent and a sugar and/or sugar alcohol; and(ii) one or more skin colour-promoting agents.The sugar is typically a mixture of glucose and sucrose.The gelling agent may be is selected from gelatin, pectin, agar, alginate and carrageenan, and mixtures thereof.The skin colour-promoting agents may comprise one or more of the carotenoids β-carotene, lycopene, zeaxanthin, lutein and astaxanthin, tyrosine, PABA and copper.