Chip Loading Structure for Integrated dPCR Detection
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Solution Overview
Problem
dPCR products require multiple sets of equipment, leading to long detection times, high costs, complex operations, and risks of reagent contamination.
Innovation Solution
A chip loading structure and analysis device that integrates a loading section, temperature control, and signal detection, reducing equipment needs, simplifying operations, and protecting detection chips during transport.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multiple sets of equipment are used for dPCR detection, then detection capability is achieved, but detection time increases and cost increases
Solution Approach 1:
The patent combines multiple functional components (loading section, temperature control section, signal detection section) into a single integrated analysis device. The loading plate body integrates chip loading, temperature control interfaces, and detection interfaces, eliminating the need for multiple separate equipment sets and reducing detection time while maintaining detection capability.
Solution Approach 2:
The loading plate body serves multiple functions simultaneously: it loads detection chips, provides temperature control interfaces, enables signal detection, and facilitates transportation. This multi-functional design reduces the number of equipment needed and streamlines the detection process, addressing the time and cost issues.
2Reliability
If multiple sets of equipment are used for dPCR detection, then detection capability is achieved, but operation complexity increases
Solution Approach 1:
By merging the loading section, temperature control section, and signal detection section into one integrated device, the patent simplifies operations. Users interact with a single loading plate body that handles all detection functions sequentially, reducing operational complexity compared to coordinating multiple separate equipment sets.
Solution Approach 2:
The analysis device is segmented into functional modules (loading section, temperature control section, signal detection section) that can operate independently but are integrated through the loading plate body. This modular segmentation makes the system easier to understand and operate while maintaining detection capability.
3Reliability
If multiple sets of equipment are used for dPCR detection, then detection capability is achieved, but reagent contamination risk increases
Solution Approach 1:
The integrated design with a single loading plate body reduces the number of interfaces and transfer points between equipment. This minimizes opportunities for reagent contamination while maintaining detection capability, as reagents remain contained within the sealed loading plate body throughout the detection process.
4Ease of operation
If detection chips are handled during transport, then chip loading is enabled, but chip safety may be compromised
Solution Approach 1:
The loading plate body integrates the chip loading function with protective structures. The accommodating space and positioning mechanisms are built into the same structure that provides mechanical protection, allowing chips to be loaded and transported safely without compromising chip integrity.
Solution Approach 2:
The loading plate body is designed with protective features that cushion and protect detection chips during handling and transport. The structural design anticipates potential mechanical stresses and incorporates elements to absorb or distribute these forces, preventing chip damage before it occurs.
Data Source
AI summary
A chip loading structure, an analysis device and an analysis system are provided. The chip loading structure includes a loading plate body having therein an accommodating space adapted to accommodate a detection chip; a first hollow area and at least one second hollow area, which penetrate to the accommodating space, are disposed on a first plate surface of the loading plate body, the first hollow area being configured to expose a reaction observation area of the detection chip, the at least one second hollow area being configured to expose at least one reagent port of the detection chip; the loading plate body is further provided with a connection portion which is detachably connectable to a transportation section in an analysis device, the transportation section being configured to transport the loading plate body.