Analysis Chip Photometry With Color Plate Wavelength Correction
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Solution Overview
Problem
Existing analysis apparatuses suffer from reduced measurement accuracy due to variations in the central wavelength of the light source during sequential measurements of reaction states and detection wavelengths, leading to inaccurate quantitative analysis.
Innovation Solution
Incorporation of a color plate within the imaging range of the analysis apparatus that changes reflectivity with wavelength, allowing simultaneous measurement of reaction states and wavelength variations, coupled with a processor that corrects measurement values based on detected wavelength variations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If measurement of reaction state and detection of measurement wavelength are performed sequentially, then the analysis apparatus can detect wavelength variation, but the analysis accuracy is lowered when central wavelength changes between measurements
Solution Approach 1:
The patent combines the reaction state measurement and wavelength detection into a single simultaneous measurement process. The area sensor captures images of both the reaction region and the color plate at the same time, eliminating the time gap between sequential measurements and ensuring that the central wavelength detected is the same as the one used for reaction state measurement.
Solution Approach 2:
The color plate serves as an intermediary element that enables wavelength detection without interfering with the reaction state measurement. By placing the color plate adjacent to the reaction region and capturing both in the same image, the system can infer wavelength information from the color plate's spectral response while simultaneously measuring the reaction state.
2Measurement precision
If a color plate is added to detect wavelength variation, then measurement precision is improved, but device complexity increases
Solution Approach 1:
The area sensor serves multiple functions: it captures images of the reaction region for quantitative analysis and simultaneously captures images of the color plate for wavelength detection. This multi-functionality eliminates the need for separate detection devices, maintaining measurement precision while avoiding additional hardware complexity.
Solution Approach 2:
The color plate utilizes wavelength-dependent color changes (spectral reflectivity characteristics) to enable wavelength detection. By capturing the color plate's appearance under the measurement light and analyzing its spectral characteristics, the system can determine the central wavelength without requiring complex optical sensors or additional light sources.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Ensures high-accuracy quantitative analysis by compensating for changes in central wavelength, thereby maintaining measurement precision even with varying illuminance distributions.
Implementation Method 1
a color plate that is arranged within the imaging range, that has a region irradiated with the measurement light L, that has characteristics in which a reflectivity changes in accordance with a wavelength of incident light
Implementation Method 2
a photometry unit including a light-emitting element that irradiates the reaction region of the analysis chip with measurement light for measuring the reaction
Data Source
AI summary
An analysis apparatus includes: a support section that supports, at a measurement position, an analysis chip having a reaction region, which holds a reagent, and used for quantitative analysis of reaction with a detection target substance that reacts with the reagent; a photometry unit including a light-emitting element that irradiates the reaction region of the analysis chip with measurement light for measuring the reaction, and an area sensor that captures an image of a predetermined imaging range including the reaction region irradiated with the measurement light; and a color plate that is arranged within the imaging range, that has a region irradiated with the measurement light, that has characteristics in which a reflectivity changes in accordance with a wavelength of incident light of the measurement light, and that is used for detecting a wavelength variation of the measurement light.