Chitosan-Activated Carbon Composite Adsorbent for Gas and Cholesterol Removal
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Solution Overview
Problem
Current activated carbons have limitations in their gas adsorption capacity and ability to adsorb cholesterol, necessitating the development of more effective formulations for treating gastrointestinal disorders and hypercholesterolaemia.
Innovation Solution
A preparation comprising activated carbon and chitosan, preferably plant chitosan from mushrooms, adsorbed onto the activated carbon, which enhances the adsorptive capacity and stability of the formulation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If activated carbon is used for gas adsorption, then gas adsorption capacity is improved, but adsorption capacity is insufficient for effective treatment
Solution Approach 1:
The patent combines activated carbon with chitosan to create a composite material that leverages the adsorption capabilities of both components. The activated carbon provides extensive surface area for gas adsorption, while chitosan adds functional groups that enhance binding capacity, resulting in a material with superior treatment effectiveness compared to activated carbon alone.
Solution Approach 2:
The patent modifies the chemical parameters of activated carbon by introducing chitosan coatings or composites. This changes the surface chemistry, pore structure, and functional group composition, thereby enhancing the adsorption capacity and selectivity for specific gases and cholesterol, improving overall treatment effectiveness.
2Quantity of substance
If activated carbon is used for cholesterol adsorption, then cholesterol adsorption is improved, but adsorption capacity is insufficient
Solution Approach 1:
The patent creates a composite of activated carbon and chitosan where chitosan's polycationic nature and functional groups synergize with activated carbon's porous structure. This composite material achieves significantly enhanced cholesterol adsorption capacity, making it effective for treating hypercholesterolaemia.
3Reliability
If higher doses of activated carbon are administered to increase adsorption capacity, then adsorption effectiveness is improved, but side effects increase
Solution Approach 1:
The patent changes the chemical and physical parameters of the adsorbent material by incorporating chitosan, which enhances adsorption capacity at the molecular level. This allows achieving the same or better treatment effectiveness at lower administered doses, thereby reducing side effects such as gastrointestinal discomfort and black stool discoloration.
4Quantity of substance
If activated carbon is used for gas adsorption, then gas adsorption is improved, but ability to adsorb cholesterol is insufficient
Solution Approach 1:
The patent develops a multi-functional adsorbent material where activated carbon maintains its gas adsorption capabilities while chitosan adds cholesterol binding functionality. The resulting composite material can simultaneously or sequentially adsorb both gases and cholesterol, providing universal treatment for multiple gastrointestinal issues.
Solution Approach 2:
By combining activated carbon and chitosan in a composite structure, the patent creates a material that inherits the gas adsorption strength of activated carbon and the cholesterol binding capability of chitosan, achieving versatile adsorption performance for multiple targets.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The preparation demonstrates increased adsorptive capacity for gases and cholesterol, providing effective treatment for gastrointestinal disorders and hypercholesterolaemia without side effects, making it suitable for pediatric and adolescent use.
Implementation Method 1
a chitosan, preferably a plant chitosan from mushrooms, adsorbed onto the activated carbon
Data Source
AI summary
A preparation in solid form comprising or, alternatively, consisting of: (i) an activated carbon; and (ii) a chitosan. preferably a plant chitosan from mushrooms, adsorbed onto said activated carbon. The chitosan has a deacety lation degree from 98% to 100% by weight. A method for preparing a preparation comprising the following steps: (I) preparing an aqueous solution of a chitosan, preferably plant chitosan from mushrooms, with a deacetylation degree from 98% to 100% by weight: (II) contacting the aqueous chitosan solution of step (I) with an activated carbon in powder form. to give a chitosan-impregnated activated carbon; (III) granulating the chitosan-impregnated activated carbon of step (II). to give a granulated impregnated activated carbon; (IV) drying the granulated impregnated activated carbon of step (III). to give said preparation. Said composition for use in the treatment of gastrointestinal disorders. Said composition for use in the treatment of hypercholesterolaemia.