Chitosan Wound Dressing Gel Formation Absorption

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Solution Overview

Problem

Existing wound care devices, particularly fibre dressings, face issues with insufficient absorption and lack of cohesion, leading to inadequate fluid management and difficulty in removing the dressing from wounds without causing trauma.

Innovation Solution

A wound care device comprising chitosan or partially de-acetylated chitin combined with an acidic substance, which does not gel initially but forms a gel when exposed to fluids, is treated with ethylene oxide to enhance absorbency and structural integrity, allowing for improved fluid retention and ease of removal.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If fibre dressings are used to treat wounds, then they can provide basic wound coverage, but they suffer from insufficient absorption of bodily fluids and lack of cohesion

Engineering Contradiction:
Improveabsorption of bodily fluidsVSAvoidcohesion of dressing
Core Design Contradiction:
Quantity of substanceVSStrength

Solution Approach 1:

The invention combines chitosan fibres with gel-forming materials to create a composite dressing structure. The chitosan fibres provide the fibrous network while the gel-forming materials (such as carboxymethyl cellulose, sodium alginate, or hydroxyethyl cellulose) provide both enhanced absorption capacity and cohesive binding, resolving the contradiction between absorption and structural integrity.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The invention modifies the physical and chemical parameters of the dressing materials by treating chitosan fibres with acids to convert them into water-swelling and water-gelling forms, and by controlling the degree of de-acetylation of chitin. These parameter changes enable the materials to transition from non-gelling to gel-forming states, simultaneously improving absorption and cohesion.

Inventive Principle:
Principle #35Parameter changes

2Strength

If gel-based dressings are used to treat wounds, then they provide cohesive structure and ease of removal, but they may have reduced absorbency compared to fibre dressings

Engineering Contradiction:
Improvecohesion of dressingVSAvoidabsorption of bodily fluids
Core Design Contradiction:
StrengthVSQuantity of substance

Solution Approach 1:

The invention creates a composite structure combining fibrous materials (chitosan or chitin-based fibres) with gel-forming materials. This composite approach allows the dressing to maintain the cohesive, non-sticking properties of gel-based dressings while incorporating the high absorption capacity of fibrous structures, thus resolving the contradiction between cohesion and absorbency.

Inventive Principle:
Principle #40Composite materials

3Quantity of substance

If chitosan fibres are treated with acid and heat to convert them into water-swelling and water-gelling form, then they gain absorption capability, but the manufacturing process becomes more complex

Engineering Contradiction:
Improveabsorption of bodily fluidsVSAvoidmanufacturing process complexity
Core Design Contradiction:
Quantity of substanceVSEase of manufacture

Solution Approach 1:

The invention performs the acid treatment and conversion of chitosan fibres into water-swelling and water-gelling forms during the manufacturing process itself, rather than requiring post-manufacturing treatment. This preliminary action integrates the functional modification into the production workflow, maintaining ease of manufacture while achieving the desired absorption properties.

Inventive Principle:
Principle #10Preliminary action

4Reliability

If the dressing is designed to gel when exposed to fluid, then it provides improved absorption and structural integrity, but it requires specific conditions (presence of acidic substance) to activate the gelling

Engineering Contradiction:
Improvestructural integrity over wear timeVSAvoidactivation conditions for gelling
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention incorporates acidic substances (such as lactic acid, acetic acid, or citric acid) directly into the dressing structure, associated with the gel-forming material. When the dressing contacts wound exudate or bodily fluids, the acidic substance is released and automatically triggers the gelling reaction without requiring external activation. This self-service mechanism ensures reliable structural integrity while minimizing device complexity.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device demonstrates increased absorbency and structural integrity over time, effectively managing wound fluids and facilitating easy removal without causing pain or trauma, while also being sterile and environmentally friendly.

Implementation Method 1

a first material which does not substantially gel when exposed to a fluid but does gel when brought together with an acidic substance and exposed to a fluid

Methodology Applied
Scientific EffectGel formation: Gel

Implementation Method 2

capable of absorbing liquid to form a swollen coherent gel

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Implementation Method 3

The wound care device demonstrates increased absorbency, making it more adept to absorb fluids that a wound care device would typically come into contact with

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Implementation Method 4

exposing the intermediate device to ethylene oxide

Methodology Applied
Scientific EffectSterilization:

Data Source

PatentEP2916879B1Wound care device
Publication Date: 2017.11.29 MEDTRADE PROD
  • EP2916879B1 patent drawingFigure 1~2
  • EP2916879B1 patent drawingFigure 3~4

AI summary

The present invention relates to a wound care device, and more specifically to an absorbent wound care device and a method for making the same. The wound care device is obtainable by bringing together a first material and an acidic substance to form an intermediate device, which first material does not substantially gel when exposed to a fluid but does gel when brought together with an acidic substance and exposed to a fluid, and exposing the intermediate device to ethylene oxide.