Chloride Persulfate Wound Composition for Pain Relief

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current treatments for periodontitis and wound healing, particularly in chronic or non-healing wounds, lack effective pain relief and sustainable, localized solutions that can be easily applied by patients, and often fail to prevent infection and promote optimal healing.

Innovation Solution

A topical composition containing a salt-shaped chloride compound, such as alkali or alkaline metal salts, combined with a persulfate oxidizing agent, which forms chloroxide or hypochlorite upon contact with moisture, providing antimicrobial and anti-inflammatory effects, and is suitable for use in creams, gels, or pastes for application on skin and mucous membranes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional wound healing treatments are used, then basic wound care is provided, but pain relief and sustainable localized treatment are insufficient

Engineering Contradiction:
Improvewound healing effectivenessVSAvoidpatient self-application capability
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent transforms the chemical state of chloride compounds from stable salts to reactive forms through controlled reaction with persulfate oxidizing agents. This parameter change enables the composition to remain stable during storage yet become highly effective upon application, resolving the contradiction between reliability and ease of operation by allowing simple patient application with sustained therapeutic effect

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent incorporates pain relief agents and antimicrobial components in advance within the adhesive composition. This preliminary action ensures that when patients apply the composition themselves, they immediately receive comprehensive treatment including pain relief, infection prevention, and wound healing promotion, eliminating the need for multiple separate treatments

Inventive Principle:
Principle #10Preliminary action

2Object-affected harmful factors

If strong oxidizing agents are used to prevent infection, then antimicrobial effect is improved, but stability during storage deteriorates

Engineering Contradiction:
Improveinfection preventionVSAvoidstorage stability
Core Design Contradiction:
Object-affected harmful factorsVSStability of the object's composition

Solution Approach 1:

The patent divides the antimicrobial system into separate stable components: chloride salts and persulfate oxidizing agents are stored separately or in stable combination, then activated upon application. This segmentation maintains storage stability while ensuring strong antimicrobial effect when needed, as the reactive species are generated only at the point of use

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses chloride salts as stable intermediaries that can be stored safely, then converted to reactive chlorine species through reaction with persulfate. This intermediary approach allows the system to maintain long-term stability while still delivering potent infection prevention when activated

Inventive Principle:
Principle #24Intermediary (Mediator)

3Duration of action of stationary object

If localized treatment is applied to achieve sustainable results, then treatment effectiveness is improved, but application complexity increases

Engineering Contradiction:
Improvesustainable treatment effectVSAvoidapplication procedure complexity
Core Design Contradiction:
Duration of action of stationary objectVSDevice complexity

Solution Approach 1:

The patent designs the composition to be self-adhering and self-sustaining. The adhesive base allows patients to apply the treatment themselves without complex procedures, while the controlled release mechanism provides sustained local action. This self-service approach achieves both simplicity of application and long-lasting effectiveness

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition accelerates wound healing, reduces pain, and prevents infection, particularly in difficult-to-heal wounds, including those on the skin and gums, while being safe for use after dental treatments and suitable for long-term application.

Implementation Method 1

at least one oxidizing agent selected from the group of persulfate compounds

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 2

a salt-form chloride compound selected from the group of alkali or alkaline earth metal salts and at least one oxidizing agent selected from the group of persulfate compounds

Methodology Applied
Scientific EffectRedox reactions: Redox Reactions

Data Source

PatentEP3218069B1Cosmetic and pharmaceutical agents for treating wounds and/or hemorrhaging of the skin, mucous membranes or the gum, in particular for example, superficial cracks (rhagaden) or perodontitis
Publication Date: 2025.01.29 BOGAERT JEAN PIERRE
  • EP3218069B1 patent drawingFigure 1
  • EP3218069B1 patent drawingFigure 2~3
  • EP3218069B1 patent drawingFigure 4~5

AI summary

The invention relates to an agent, in particular a cosmetic and/or pharmaceutical agent, containing an active composition and optionally an adhesion composition, said active composition containing at least one organic or inorganic chlorine compound and at least one oxidation agent, for use in the treatment of wounds and/or hemorrhaging of the skin, mucous membranes or the gums, in particular in the absence of canker sores.