Chlorine Dioxide Tooth Whitening Composition

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Solution Overview

Problem

Current tooth whitening products, particularly those using hydrogen peroxide or carbamide peroxide, often cause side effects such as tooth sensitivity, soft tissue irritation, and tooth surface changes due to dehydration and acidic pH, and exhibit rebound phenomena where stains reappear after treatment.

Innovation Solution

A bleaching composition comprising chlorine dioxide as a non-cytotoxic primary bleaching agent, combined with a second bleaching agent and a thickener component, which minimizes irritation and damage to hard tooth tissues while maintaining effective whitening efficacy, is used to whiten teeth.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If high concentrations of hydrogen peroxide or carbamide peroxide are used for tooth whitening, then bleaching efficacy is improved, but tooth sensitivity and soft tissue irritation increase

Engineering Contradiction:
Improvebleaching efficacyVSAvoidtooth sensitivity and soft tissue irritation
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameter from peroxide-based bleaching agents to chlorine dioxide, maintaining effective bleaching capability while reducing cytotoxicity. Chlorine dioxide achieves comparable whitening efficacy without the severe side effects of high-concentration peroxides, including reduced tooth sensitivity and soft tissue irritation.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs a gel formulation that can be applied and removed, allowing for controlled, temporary contact with the teeth. This disposable-like application approach enables effective bleaching while minimizing prolonged exposure that causes sensitivity and irritation.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Stability of the object's composition

If acidified and thickened peroxide formulations are used for tooth whitening, then peroxide stabilization is improved, but dehydration of tooth tissues occurs causing sensitivity

Engineering Contradiction:
Improveperoxide stabilizationVSAvoidtooth dehydration and sensitivity
Core Design Contradiction:
Stability of the object's compositionVSObject-affected harmful factors

Solution Approach 1:

The patent uses a gel formulation that provides temporary, controlled stabilization without requiring prolonged acidified conditions. The gel can be applied, stabilized during the treatment period, and then removed, avoiding cumulative dehydration effects while maintaining peroxide stability during the treatment window.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The gel acts as an intermediary carrier that provides stabilization without requiring the same acidified conditions as peroxide formulations. This intermediary medium achieves stability while being less dehydrating to tooth tissues.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Loss of time

If professional strength peroxide treatments are used for rapid whitening, then treatment time is reduced, but gingival irritation and ingestion risk increase

Engineering Contradiction:
Improvetreatment timeVSAvoidgingival irritation and ingestion risk
Core Design Contradiction:
Loss of timeVSObject-affected harmful factors

Solution Approach 1:

The patent employs a gel formulation designed for controlled, short-duration application that can be safely removed. This approach enables rapid whitening treatment while minimizing the time harmful agents remain in contact with gingival tissues, reducing irritation and ingestion risk.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent extracts the harmful peroxide components and replaces them with chlorine dioxide in a gel formulation. This extraction of the problematic substance allows for rapid treatment without the severe gingival irritation and ingestion risks associated with professional-strength peroxide treatments.

Inventive Principle:
Principle #2Taking out (Extraction)

4Productivity

If peroxide-based whitening products are used, then intrinsic staining is removed, but rebound phenomenon occurs where stains reappear

Engineering Contradiction:
Improvestain removal capabilityVSAvoidduration of whitening effect
Core Design Contradiction:
ProductivityVSDuration of action of stationary object

Solution Approach 1:

The patent changes the chemical mechanism from peroxide oxidation to chlorine dioxide bleaching. This parameter change in the bleaching agent chemistry produces more stable results with reduced rebound, as chlorine dioxide effectively removes intrinsic stains without the same degree of temporary effect seen with peroxide treatments.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves rapid and extensive tooth whitening with reduced side effects, such as sensitivity and irritation, and potentially lower rebound rates compared to peroxide-based products, while maintaining enamel and dentin microhardness and surface integrity.

Implementation Method 1

Intrinsic stain removal can be achieved by a variety of methods including use of peroxides or peroxide analogs, with or without chemical, light or heat activation, to bleach the stains. This method oxidizes organic compounds within the enamel and dentin, thereby changing colored materials to non-colored materials

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 2

They also contain carbomers (for thickening and control) and acidifiers (for peroxide stabilization in aqueous solution)

Methodology Applied
Scientific EffectThickening:

Data Source

PatentEP2313066B1Tooth whitening compositions and methods
Publication Date: 2015.11.25 BASF CORPORATON
  • EP2313066B1 patent drawingFigure 1
  • EP2313066B1 patent drawingFigure 2
  • EP2313066B1 patent drawingFigure 3A~3C

AI summary

A non-cytotoxic chlorine dioxide composition and a mixed agent bleaching composition for tooth whitening are disclosed. Methods of use are also provided.