Chromamide–Scott Protein Mixtures for Stable Pest Control

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Solution Overview

Problem

Existing pesticidal compositions derived from Chromobacterium species lack synergistic effects and stability, leading to inefficiencies in controlling pests and potential resistance development.

Innovation Solution

A synergistic insecticidal composition comprising chromamide compounds (MW 860, 874A, 874B, 876) and Scott proteins (Scott 1, 2, 3) in a carrier, optionally with additional insecticides, for modulating pest infestation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing pesticidal compositions derived from Chromobacterium species are used, then pest control function is provided, but synergistic effects and stability are lacking leading to inefficiencies and resistance development

Engineering Contradiction:

Improveinsecticidal efficacyVSAvoidcomposition stability

Core Design Contradiction:

ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent combines multiple Chromobacterium metabolites (chromamide compounds, violacein, and Scott proteins) into a single synergistic composition. This merging of multiple bioactive components creates enhanced insecticidal efficacy through synergistic interactions while improving overall composition stability compared to single-compound formulations.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite pesticidal composition containing chromamide compounds, violacein, and Scott proteins derived from Chromobacterium species. This composite formulation leverages the complementary properties of each component to achieve both superior insecticidal activity and enhanced stability, resolving the contradiction between efficacy and stability.

Inventive Principle:

Principle #40Composite materials

2Reliability

If existing pesticidal compositions are used, then pest control is achieved, but resistance development occurs reducing long-term effectiveness

Engineering Contradiction:

Improvepest control effectivenessVSAvoidlong-term control duration

Core Design Contradiction:

ReliabilityVSDuration of action of moving object

Solution Approach 1:

By combining multiple metabolites with different modes of action (chromamide compounds, violacein, and Scott proteins), the composition attacks pests through multiple mechanisms simultaneously. This multi-target approach prevents resistance development and maintains long-term effectiveness, extending the duration of actionable control.

Inventive Principle:

Principle #5Merging (Combining)

3Device complexity

If single-compound formulations are used, then formulation simplicity is maintained, but synergistic effects are lost reducing insecticidal activity

Engineering Contradiction:

Improveformulation complexityVSAvoidinsecticidal activity

Core Design Contradiction:

Device complexityVSReliability

Solution Approach 1:

The patent merges multiple Chromobacterium metabolites into a single integrated formulation that produces synergistic effects. While the composition contains multiple components, they are formulated together as one product, maintaining relative simplicity while achieving enhanced insecticidal activity through synergistic interactions between components.

Inventive Principle:

Principle #5Merging (Combining)

Data Source

PatentUS20250287954A1Method and composition of synergistic insecticidal mixtures

Publication Date: 2025.09.18 PFG HOLDING CORP

AI summary

The present disclosure provides a synergistic insecticidal composition comprising: one or more chromamide compounds; and one or more Scott proteins disposed in a carrier.