Liquid Chromatograph Pressure Failure Detection Using Damper Capacity
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Solution Overview
Problem
Existing liquid chromatograph systems face challenges in accurately detecting liquid sending failures due to internal capacities of components acting as dampers, which vary by system configuration, leading to unstable pressure fluctuations and inefficient analysis.
Innovation Solution
A liquid chromatograph system that includes a pressure sensor, a damper capacity holder, a reference value determiner, and a liquid sending failure detector, which uses the damper capacity to set a reference value for pressure fluctuations and accurately detects failures by analyzing pressure changes during the liquid sending pump's operation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stability of the object's composition
If internal capacities of components (sample injector, separation column, detector, pipes) are used as dampers, then pressure fluctuation is reduced, but liquid sending failure detection accuracy deteriorates
Solution Approach 1:
The system dynamically adapts the reference value for failure detection based on the actual damper capacity detected in real-time, rather than using a fixed reference value. This allows the detection threshold to change according to system conditions, maintaining accuracy despite varying pressure stability characteristics
Solution Approach 2:
The invention changes the detection parameter from a fixed reference value to a variable reference value that depends on the damper capacity. By detecting the actual damper capacity first and then setting the reference value accordingly, the system achieves accurate failure detection across different operating conditions
2Ease of operation
If a fixed reference value is used for pressure fluctuation evaluation, then detection simplicity is improved, but failure detection accuracy deteriorates
Solution Approach 1:
The system performs self-characterization by automatically detecting its own damper capacity and using this information to set the appropriate reference value for failure detection. This eliminates the need for manual configuration or external calibration, maintaining operational simplicity while improving accuracy
Solution Approach 2:
The system performs preliminary detection of the damper capacity before conducting failure detection. This preliminary action establishes the correct reference value in advance, ensuring that the subsequent failure detection is accurate without requiring complex real-time adjustments
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration allows for precise detection of liquid sending failures, accounting for varying internal capacities, thereby improving the reliability of analysis data and reducing wasteful acquisition of data due to pulsation and pressure instability.
Implementation Method 1
a pressure sensor for detecting a liquid sending pressure in the analysis flow path
Implementation Method 2
a damper capacity holder that holds an internal capacity of a system through which a mobile phase from the liquid sending pump flows as a damper capacity
Data Source
AI summary
A liquid chromatograph includes a liquid sending pump for sending a mobile phase, a sample injector that injects a sample into an analysis flow path through which a mobile phase from the liquid sending pump flows, a separation column that is provided on the analysis flow path and is to separate a sample that has been injected into the analysis flow path by the sample injector into components, a pressure sensor for detecting a liquid sending pressure in the analysis flow path located at a position farther upstream than the separation column, a damper capacity holder that holds an internal capacity of a system through which a mobile phase from the liquid sending pump flows as a damper capacity, a reference value determiner configured to determine a reference value of a fluctuation range of the liquid sending pressure when a liquid sending failure of the liquid sending pump occurs, using at least the damper capacity held by the damper capacity holder, and a liquid sending failure detector that is configured to periodically acquire a liquid sending pressure detected by the pressure sensor, obtain a fluctuation range of the liquid sending pressure in a certain driving period of the liquid sending pump and detect a liquid sending failure using the obtained fluctuation range and the reference value determined by the reference value determiner.