Liquid Chromatograph Auto-Sampler Pretreatment Control via External Variables

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Solution Overview

Problem

Conventional liquid chromatograph systems lack the ability to easily control pretreatment operations for auto-samplers, making it difficult for both skilled and unskilled users to perform serial analyses with varying pretreatment requirements, as the pretreatment programs are complex and time-consuming to create.

Innovation Solution

An analyzing system with an auto-sampler that allows users to create and execute pretreatment programs using external variables, enabling easy control of the auto-sampler operations through an edit screen, batch table display, and serial analysis execution, allowing users to enter numerical values or commands in external-variable setting fields without rewriting the program.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a pretreatment program is created to control auto-sampler operations for serial analysis, then the analysis capability is improved, but the program complexity and creation time increase significantly

Engineering Contradiction:
Improveanalysis capabilityVSAvoidprogram complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The pretreatment program is segmented into multiple independent screens (first screen for basic settings, second screen for detailed pretreatment parameters). This allows users to access only the necessary settings for their specific analysis needs, reducing the perceived complexity while maintaining full functionality.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A batch table is introduced as an intermediary between user input and program execution. The batch table stores analysis conditions and automatically retrieves corresponding pretreatment parameters, serving as a mediator that simplifies user interaction while managing complex program logic in the background.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If a comprehensive pretreatment program is created to handle various pretreatment modes, then the versatility is improved, but the time required to create and rewrite the program increases

Engineering Contradiction:
Improvepretreatment versatilityVSAvoidprogram creation time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

Multiple pretreatment programs for different analysis modes are prepared in advance and stored in the system. When a user initiates an analysis, the system automatically selects and applies the appropriate pre-prepared program based on the analysis type, eliminating the need for users to create programs from scratch each time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system design allows a single integrated interface to handle multiple pretreatment modes (condensation, dilution, reagent addition, etc.) through different screens and batch table configurations. This universal interface provides access to all pretreatment functions without requiring separate programs for each mode.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Extent of automation

If detailed pretreatment parameters are hardcoded in the program, then the program functionality is improved, but the ease of operation for unskilled users deteriorates

Engineering Contradiction:
Improveprogram functionalityVSAvoiduser operation ease
Core Design Contradiction:
Extent of automationVSEase of operation

Solution Approach 1:

The interface dynamically adapts to user needs by displaying different screens based on the analysis type selected in the batch table. The system automatically shows only the relevant pretreatment screens for each analysis mode, making the interface dynamic rather than static, which improves ease of operation while maintaining full functionality.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system automatically retrieves pretreatment parameters from the batch table based on the analysis conditions specified by the user. This self-service mechanism eliminates the need for users to manually configure complex parameters, as the system automatically matches the analysis type with the appropriate pretreatment settings.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS8418533B2Analyzing system for liquid chromatograph and control program for the same system
Publication Date: 2013.04.16 SHIMADZU CORP
  • US8418533B2 patent drawing
  • US8418533B2 patent drawing
  • US8418533B2 patent drawing

AI summary

The present invention provides an analyzing system with which a serial analysis inclusive of a pretreatment can be easily performed in a liquid chromatograph, and even unskilled users can perform a desired analysis. The analyzing system according to the present invention includes: an edit screen display section 31 for displaying an edit screen for allowing a user to create a pretreatment program using an external variable; a batch table display section 32 for displaying a batch table used for serially executing a plurality of analyses, the batch table having an external-variable setting field for allowing the user to enter the aforementioned external variable; and a serial analysis execution section 33 for serially executing each of the analyses inclusive of a pretreatment operation of an auto-sampler according to the pretreatment program and the batch table.