Liquid Chromatography Column Device with Detachable Cover

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Solution Overview

Problem

Conventional column devices for liquid chromatography require labor-intensive operations to replace the column device, as both inlet and outlet pipes need to be unscrewed from the end caps, making the process cumbersome and prone to errors.

Innovation Solution

The design separates the end cap's column body closing and sealing function from the joint member's pipe connection function, allowing the column body and end caps to be housed in a bottomed cylindrical case with a detachable cover member, enabling easy attachment and detachment by operating the cover member alone.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If inlet and outlet pipes are screwed to end caps, then connection reliability is improved, but replacement operation complexity increases

Engineering Contradiction:
Improveconnection reliabilityVSAvoidreplacement operation complexity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The device is divided into a reusable outer assembly (case with inlet/outlet pipes) and a replaceable inner assembly (column device). This segmentation allows the column to be replaced independently without disturbing the pipe connections, resolving the contradiction between maintaining reliable connections and simplifying replacement operations.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The case acts as an intermediary component that remains fixed while containing both the column device and joint members. This intermediary structure enables the column to be replaced without unscrewing pipes, as the case provides a stable interface between the fixed piping system and the replaceable column assembly.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If end cap integrates both closing and pipe connection functions, then device structure is simplified, but replacement operation requires multiple unscrewing locations

Engineering Contradiction:
Improvedevice structureVSAvoidreplacement operation
Core Design Contradiction:
Device complexityVSEase of operation

Solution Approach 1:

The integrated end cap functions are separated into distinct components: the case provides the closing function while the joint members handle pipe connections. This functional segmentation allows the column device (with end caps) to be replaced as a single unit without unscrewing multiple pipe connections, reducing operational complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The case merges the functions of containing the column device, housing the joint members, and providing the structural closing. This merging creates a unified replacement unit that simplifies the replacement operation to a single location, while maintaining clear functional separation between the case and column device.

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If column device is replaced by unscrewing two pipe joints, then connection integrity is maintained, but operation time and labor increase

Engineering Contradiction:
Improveconnection integrityVSAvoidreplacement efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The system is segmented into a permanent piping system (attached to the case) and a replaceable column assembly. This segmentation ensures connection integrity is maintained in the fixed piping system while dramatically improving replacement efficiency, as the column can be swapped without disturbing any pipe joints.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The joint members are pre-installed on the case with inlet and outlet pipes already connected. This preliminary action ensures connection integrity is established before column replacement, allowing the column device to be replaced quickly by simply removing and reattaching the column to the pre-prepared joint members.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP2975398B1Column device for liquid chromatography and liquid chromatography device
Publication Date: 2018.02.21 SEKISUI MEDICAL CO LTD
  • EP2975398B1 patent drawingFigure 1
  • EP2975398B1 patent drawingFigure 2
  • EP2975398B1 patent drawingFigure 3

AI summary

A cylindrical column body (101) holds a filler. A pair of end caps (105, 106) covers both ends of the column body (101) and has a flow hole for a carrier liquid (111, 112) arranged in the center thereof. An end surface on the side of a large diameter portion (113a, 114a) of a pair of columnar joint members (113, 114) contacts an end surface of the pair of end caps (105, 106) and also has a communication hole (115, 116) arranged in the center thereof. A sealing member (117, 118) is arranged on a contact surface between the end cap (105, 106) and the joint member (113, 114). A bottomed cylindrical case (121) accommodates the pair of end caps (105, 106) and a large diameter portion of the pair of joint members (113, 114) in an engaged state. A cover member (124) is detachably installed on a side of an opening of the case (121).