Chromatography Column Base Assembly with Hydraulic Lifting

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Conventional chromatography and synthesis columns require complex, time-intensive, and resource-heavy maintenance procedures, posing safety risks and potential damage to components due to the heavy weight and low ground clearance, which complicates the removal and reassembly of the bottom plate and bed components.

Innovation Solution

A base assembly with hydraulic lifting mechanisms and a rigid swing arm for chromatography and synthesis columns, allowing for precise control and safe lifting and lowering of the column frame, enabling easier disassembly and reassembly by pivoting the bottom plate along a horizontal plane, and using telescoping legs for stable movement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If conventional columns are designed with heavy bottom plates (about 1,500 pounds) and low ground clearance, then structural stability is improved, but maintenance complexity and safety risks increase significantly

Engineering Contradiction:
Improvestructural stabilityVSAvoidmaintenance complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

A base assembly with hydraulic lifting mechanisms serves as an intermediary device between the column and the ground. This base assembly includes a frame with legs that can be positioned under the column, and hydraulic cylinders that provide controlled lifting force, eliminating the need for manual handling of the heavy bottom plate while maintaining structural stability during maintenance operations

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

Hydraulic lifting mechanisms are integrated into the base assembly to provide controlled vertical movement of the column. The hydraulic system enables precise elevation and lowering of the heavy column components, making maintenance operations safer and easier without compromising the structural integrity of the column

Inventive Principle:
Principle #29Pneumatics and hydraulics

2Ease of operation

If manual removal methods using threaded rods and jack screws are used to elevate the bottom plate, then the heavy bottom plate can be removed, but the process becomes time-intensive and requires multiple coordinated operators

Engineering Contradiction:
Improvebottom plate removalVSAvoidmaintenance time
Core Design Contradiction:
Ease of operationVSLoss of time

Solution Approach 1:

The base assembly with hydraulic lifting mechanisms enables a single operator to easily elevate and remove the bottom plate without requiring multiple people to coordinate manual operations. The hydraulic system performs the heavy lifting work automatically, making the maintenance process self-sufficient and dramatically reducing the time required for bottom plate removal and reinstallation

Inventive Principle:
Principle #25Self-service

3Ease of operation

If lift devices are used to move the heavy bottom plate, then the plate can be elevated for removal, but imprecise operation of lift devices can cause damage to column components

Engineering Contradiction:
Improvebottom plate movementVSAvoidcomponent safety
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The base assembly acts as a controlled intermediary between the lift device and the column components. It provides a stable platform with guided movement paths that ensure precise positioning during bottom plate removal and reinstallation, preventing accidental collisions or misalignment that could damage sensitive column components while still enabling easy operation

Inventive Principle:
Principle #24Intermediary (Mediator)

4Stability of the object's composition

If columns are positioned low to the ground for stability, then structural support is improved, but ground clearance becomes insufficient for maintenance equipment and operations

Engineering Contradiction:
Improvecolumn stabilityVSAvoidmaintenance accessibility
Core Design Contradiction:
Stability of the object's compositionVSEase of operation

Solution Approach 1:

The base assembly introduces dynamic vertical adjustment capability to the previously static column position. The hydraulic lifting mechanisms allow the column to be elevated to various heights as needed for maintenance operations, while returning to a stable low position when not in use. This dynamic positioning resolves the conflict between maintaining structural stability and providing adequate ground clearance for maintenance equipment and operators

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS11745119B2Chromatography and synthesis column apparatus and method of assembly
Publication Date: 2023.09.05 ASAHI KASEI BIOPROCESS AMERICA INC
  • US11745119B2 patent drawing
  • US11745119B2 patent drawing
  • US11745119B2 patent drawing

AI summary

Chromatography and synthesis columns, assemblies, components, and methods of assembly and disassembly are disclosed including a support assembly having lifting mechanisms in each of the legs to raise and lower a frame secured to the column, a swing arm and/or carriage guiding movement of a bottom plate of the column, a bolt-free coupling between the main tube and bottom plate of the column, and upper and lower slurry ports in the main tube of the column.