Extracorporeal Circulation Management Device Oxygen Consumption Calculation

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Solution Overview

Problem

The oxygen saturation of blood supplied by an extracorporeal circulation device does not remain constant, making it difficult to accurately determine oxygen consumption in patients, as the oxygen saturation in the arterial-side tube can differ from that in the venous-side tube after oxygen consumption.

Innovation Solution

An extracorporeal circulation management device that stores and compares time-course information of blood state data from both the oxygenator and the patient, using in-body passing time information to select appropriate data points for comparison, allowing for accurate determination of oxygen consumption and oxygen delivery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If oxygen saturation of blood supplied by the oxygenator is monitored continuously, then the oxygen delivery function is provided, but the oxygen saturation value fluctuates and cannot be used for accurate oxygen consumption calculation

Engineering Contradiction:
Improveoxygen delivery functionVSAvoidoxygen saturation value
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The system performs preliminary actions by storing multiple pieces of state information with time-course data before comparison. It proactively manages the temporal relationship between blood samples by recording when each sample was taken and storing it until a matching pair is identified, allowing the system to prepare data for future comparison rather than relying on instantaneous readings

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system uses feedback by continuously monitoring oxygen saturation and using this information to adjust and identify matching blood samples. The oxygen saturation value serves as feedback that helps the system determine which stored samples should be compared, creating a closed-loop system that refines its measurements based on ongoing observations

Inventive Principle:
Principle #23Feedback

2Productivity

If arterial-side and venous-side oxygen saturation are compared directly, then oxygen consumption calculation is attempted, but the values do not correspond due to time delay in blood circulation

Engineering Contradiction:
Improveoxygen consumption calculationVSAvoidoxygen saturation comparison accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system adds a temporal dimension to the comparison by introducing time-course information and in-body passing time. Instead of comparing oxygen saturation values in a single moment, the system compares values across different time points, accounting for the circulation delay. This transforms a one-dimensional comparison into a multi-dimensional analysis that includes time as a critical parameter

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The in-body passing time information acts as an intermediary that connects the arterial-side and venous-side measurements. Rather than directly comparing oxygen saturation values, the system uses the in-body passing time as a mediator to identify which arterial sample corresponds to which venous sample, ensuring accurate pairing despite circulation delays

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentEP3238763B1Extracorporeal circulation management device and extracorporeal circulation device including same
Publication Date: 2019.12.04 TERUMO KK
  • EP3238763B1 patent drawingFigure 1
  • EP3238763B1 patent drawingFigure 2
  • EP3238763B1 patent drawingFigure 3

AI summary

[Object] Providing an extracorporeal circulation management device and so forth by which the oxygen consumption or the like in a patient regarding blood supplied from an oxygenator or the like can be correctly determined. [Solution] An extracorporeal circulation management device 10 carries out storing 52 of plural pieces of first state information of blood supplied from an oxygenator unit 2 with time-course information and plural pieces of second state information of blood introduced into the oxygenator unit with time-course information, has in-body passing time information 42, and selects the first state information and the second state information as comparison targets from the plural pieces of first state information and the plural pieces of second state information based on the in-body passing time information when comparing any of the plural pieces of first state information and any of the plural pieces of second state information.