Percutaneous Circulatory Support Device Reducing Hemolysis
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Solution Overview
Problem
Percutaneous circulatory support devices often cause hemolysis and related complications due to the rupture or destruction of blood cells, leading to thrombi formation and other issues during operation.
Innovation Solution
A percutaneous circulatory support device featuring a rotatable impeller and liquid carrier with outwardly extending menisci formed by a liquid, driven by a motor and driven magnet, which reduces hemolysis by creating positive pressure and inhibiting blood from entering small voids, and includes a flattened impeller shape and elongated apertures to prevent blood pooling.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a percutaneous circulatory support device operates to provide circulatory support, then circulatory function is improved, but hemolysis occurs due to blood cell rupture
Solution Approach 1:
A liquid carrier containing a lubricating liquid is introduced as an intermediary between the impeller and the blood. The liquid carrier rotates with the impeller and distributes the lubricating liquid to reduce direct contact and friction between blood and device surfaces, thereby reducing hemolysis while maintaining circulatory support function
Solution Approach 2:
The device changes the physical parameters of the blood environment by introducing a lubricating liquid that modifies surface properties and reduces friction. This parameter change (from dry/high-friction contact to lubricated/low-friction contact) reduces blood cell rupture while maintaining the mechanical function of the device
2Productivity
If the impeller rotates to move blood through the device, then blood flow is improved, but friction increases causing hemolysis
Solution Approach 1:
The device uses a hydraulic lubrication system where a liquid carrier rotates with the impeller and distributes lubricating liquid to the blood flow path. This hydraulic approach reduces friction between moving parts and blood, allowing high-speed rotation for effective blood flow while minimizing hemolysis
Solution Approach 2:
The lubricating liquid acts as an intermediary substance between the rotating impeller and the blood, reducing direct frictional contact. The liquid carrier serves as the delivery mechanism, ensuring continuous lubrication during high-speed rotation to maintain productivity while reducing harmful friction effects
3Ease of operation
If the device structure is simplified for percutaneous insertion, then ease of operation is improved, but small voids create blood pooling and thrombosis
Solution Approach 1:
The lubricating liquid in the liquid carrier serves as an intermediary that prevents blood from pooling in small voids and crevices of the simplified device structure. The liquid creates a protective film that eliminates stagnant blood zones, reducing thrombosis risk while maintaining the simplified percutaneous design
Solution Approach 2:
The introduction of lubricating liquid changes the surface parameters of device voids from hydrophilic/blood-retentive to hydrophobic/blood-repellent surfaces. This parameter change prevents blood pooling in the simplified device structure, eliminating thrombosis risk while maintaining ease of percutaneous insertion
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively reduces hemolysis and thrombosis by creating a seal and reducing friction, facilitating safer and more efficient blood flow through the circulatory support system.
Implementation Method 1
the liquid carrier being rotatable relative to the impeller housing to cause the liquid to form outwardly extending menisci at a plurality of apertures of the liquid carrier
Implementation Method 2
a motor operatively coupled to the impeller and rotating the impeller relative to the impeller housing
Data Source
AI summary
A percutaneous circulatory support device includes an impeller disposed within an impeller housing. The impeller is rotatable relative to the impeller housing to cause blood to flow through the percutaneous circulatory support device. The device further includes a liquid carrier carrying a liquid. The liquid carrier is rotatable relative to the impeller housing to cause the liquid to form outwardly extending menisci at a plurality of apertures of the liquid carrier.