Cistanche Ginkgo Extract Ratio for Memory Improvement
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Solution Overview
Problem
Current methods for improving short- and long-term memory are inadequate, as existing dietary supplements do not effectively address memory loss or retention, and there is a need for additional compositions that can reverse, slow, or prevent memory decline.
Innovation Solution
A composition comprising Cistanche and Ginkgo extracts, administered in specific weight ratios, is used to improve memory, with Cistanche extract from the root and Ginkgo extract from the leaves, potentially enhancing neuronal health and memory formation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing dietary supplements are used to improve memory, then some level of brain health support is provided, but they do not effectively reverse or prevent memory loss
Solution Approach 1:
The patent combines Cistanche extract and Ginkgo extract in a composite formulation with a specific weight ratio greater than 2.5:1. This composite approach leverages the synergistic effects of both extracts, where Cistanche provides neuroprotective compounds and Ginkgo contributes to cerebral blood flow and cognitive function, creating a more effective memory improvement solution than either extract alone
Solution Approach 2:
The patent specifies a critical parameter threshold for the weight ratio of Cistanche to Ginkgo extract greater than 2.5:1. This parameter optimization ensures the composition achieves maximum efficacy for preventing and reversing memory loss, transforming the formulation from a simple mixture to a precisely optimized therapeutic composition
2Reliability
If a combination of Cistanche and Ginkgo extracts is used, then synergistic benefits for neuronal health are achieved, but the composition complexity increases
Solution Approach 1:
The patent creates a composite material system combining Cistanche extract and Ginkgo extract in a specific weight ratio greater than 2.5:1. This composite formulation achieves synergistic effects for neuronal health and memory improvement while maintaining a relatively simple two-component structure that avoids excessive formulation complexity
Solution Approach 2:
The Cistanche-Ginkgo composite composition serves multiple functions simultaneously: it supports neuronal cell signaling, improves memory formation and retention, and provides neuroprotective effects. This multi-functionality is achieved through the complementary mechanisms of both extracts working together in the optimized ratio
Data Source
AI summary
A method and composition useful for improving memory of a subject are disclosed. The method comprises the step of administering the composition to the subject. The composition consists essentially of Cistanche extract and Ginkgo extract (e.g. as actives). In a first general embodiment, the extracts are present in a weight ratio (Cistanche to Ginkgo; or “C:G”) that is >2.5:1. In a second general embodiment, the extracts are present in a weight ratio that is <2.5:1. In embodiments of the first general embodiment, the composition comprises about 72-99 weight percent (wt. %) Cistanche tubulosa extract and about 1-28 wt. % Ginkgo biloba extract. In embodiments of the second general embodiment, the composition comprises about 50-70 wt. % Cistanche tubulosa extract and about 30-50 wt. % Ginkgo biloba extract. The Cistanche tubulosa extract is generally obtained from root material and the Ginkgo biloba extract is generally obtained from leaf material. The composition may also include inactives.