Citrate Detector Optical Monitoring Blood Processing
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Solution Overview
Problem
Current blood processing systems lack effective methods to accurately detect and monitor citrate levels in replacement fluids, which can be harmful if excessively infused, leading to potential complications for donors or patients.
Innovation Solution
A citrate detection system utilizing a light source emitting a wavelength absorbed by citrate, combined with a light detector to generate signals indicative of citrate presence, is integrated into the blood processing system, allowing for real-time monitoring and prevention of excessive citrate infusion through a controller that compares signals to baseline values.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a light source emitting a wavelength absorbed by citrate is used with a light detector, then citrate detection precision is improved, but device complexity increases
Solution Approach 1:
The citrate detection system is segmented into distinct functional modules: a light source module emitting at a specific wavelength absorbed by citrate, a flow conduit module for fluid transport, and a light detector module for signal reception. This segmentation allows each component to be optimized independently while maintaining overall system precision without excessive complexity.
Solution Approach 2:
The blood processing system is designed to perform multiple functions: it can detect citrate in replacement fluids, monitor anticoagulant levels, and process blood components. The optical detection system serves as a universal monitoring mechanism that can identify various substances based on their light absorption characteristics, reducing the need for separate detection systems for each function.
2Reliability
If real-time citrate monitoring is implemented, then safety is improved, but device complexity increases
Solution Approach 1:
The system implements real-time feedback monitoring where the light detector continuously measures light absorption by citrate in the replacement fluid and provides immediate signals to the controller. This feedback mechanism enables real-time safety monitoring and alerts without requiring complex predictive algorithms or multiple redundant systems.
Solution Approach 2:
The system performs preliminary detection of citrate levels before the replacement fluid is infused into the patient. By detecting citrate presence in advance through optical measurement, the system can prevent harmful infusion before it occurs, enhancing safety without requiring complex intervention mechanisms during the infusion process.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Ensures accurate detection and prevention of excessive citrate infusion, thereby safeguarding donors and patients by providing real-time alerts and ensuring proper fluid connections, thus enhancing the safety and efficiency of blood processing procedures.
Implementation Method 1
a light source configured to emit a light toward and into the replacement fluid flow conduit, the light having a wavelength absorbed by citrate
Implementation Method 2
a light detector configured to receive at least a portion of the light from the light source exiting the replacement fluid flow conduit and generate a signal indicative of the presence or absence of citrate
Data Source
AI summary
The present invention relates to a blood processing system (10)comprising a replacement fluid flow conduit (48), and a citrate detector (42) comprising a light source (58) configured to emit a light toward and into the replacement fluid flow conduit (48), the light having a wavelength absorbed by citrate, but at least partially transmitted by the replacement fluid flow conduit (48); and a light detector (46) configured to receive at least a portion of the light from the light source (44) exiting the replacement fluid flow conduit (48) and generate a signal indicative of the presence or absence of citrate in the replacement fluid flow conduit (48) based, at least in part, on the amount of light received by the light detector (46). The present invention also relates to a durable assembly for such blood processing system (10), and to a method of monitoring fluid within such blood processing system (10).