Citric Acid Composition for Muscle Mass Maintenance
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Solution Overview
Problem
There is a need for a composition that effectively increases muscle mass and prevents disuse syndrome, particularly in aged individuals and long-term bedridden persons, as existing solutions are inadequate in addressing muscle atrophy and rehabilitation effectively.
Innovation Solution
A composition containing citric acid, its salts, or hydrates, such as sodium citrate and potassium citrate, which are administered to increase muscle mass, prevent disuse syndrome, and enhance rehabilitation by promoting muscle growth and renal function without requiring high-intensity exercise.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If bed rest is continued for a certain period of time, then disease or injury treatment is achieved, but muscle strength decreases and muscles atrophy
Solution Approach 1:
The patent introduces a food composition containing citric acid, oligosaccharide acid, and calcium as an intermediary substance that mediates between bed rest and muscle maintenance. This composition suppresses muscle atrophy and maintains muscle strength during prolonged bed rest, allowing treatment to proceed while preventing the harmful effect of muscle weakening
Solution Approach 2:
The patent changes the biochemical parameters of the body by introducing specific substances (citric acid, oligosaccharide acid, calcium) that alter metabolic processes. These parameter changes enable muscle maintenance during bed rest by affecting protein synthesis, calcium metabolism, and energy utilization pathways
2Stability of the object's composition
If conventional food compositions are used to suppress muscle atrophy, then some muscle maintenance is achieved, but muscle mass increase is insufficient
Solution Approach 1:
The patent creates a composite food composition combining multiple active ingredients (citric acid, oligosaccharide acid, and calcium) that work synergistically. This composite approach achieves both muscle mass maintenance and increase by leveraging the complementary effects of different substances on protein synthesis and muscle metabolism
Solution Approach 2:
The patent modifies metabolic parameters by introducing citric acid which affects the citric acid cycle and protein synthesis pathways. This biochemical parameter change enables not only muscle maintenance but also net muscle mass increase during bed rest periods
3Quantity of substance
If high-intensity exercise is performed to increase muscle mass, then muscle growth is achieved, but energy consumption and recovery time increase
Solution Approach 1:
The patent replaces the mechanical system of high-intensity exercise with a biochemical system involving citric acid, oligosaccharide acid, and calcium. This substitution achieves muscle mass increase without the energy consumption and physical stress associated with intensive exercise, making it suitable for bedridden individuals
4Quantity of substance
If citric acid and its salts are administered, then muscle mass increases and renal function improves, but dosage control is required
Solution Approach 1:
The patent optimizes the dosage parameters by specifying citric acid content of 0.1-2.0 g/day and salts of citric acid of 1.0-5.0 g/day. These parameter adjustments ensure effective muscle mass increase and renal function improvement while maintaining safety and simplifying dosage control for practical application
Data Source
AI summary
Provided is a composition for increasing muscle mass in a mammal, the composition including citric acid, a salt of citric acid, a hydrate thereof, or a mixture thereof.