Citrus Polyphenol Lipolytic Composition Without Synephrine
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Solution Overview
Problem
Current dietary supplements with lipolytic activity often have adverse cardiovascular and cerebrovascular effects due to the inclusion of molecules like synephrine, and other lipolytic agents like theophylline and caffeine can be excessive when consumed naturally, leading to unhealthy dietary imbalances.
Innovation Solution
A composition with lipolytic activity derived from citrus fruits, specifically comprising polyphenols such as flavonoids, anthocyanins, phenolic acids, and caffeine, without synephrine, formulated to enhance fat burning and physical performance while being safe and free from undesirable side effects.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Power
If synephrine is included in dietary supplements for lipolytic activity, then fat burning effect is improved, but cardiovascular and cerebrovascular side effects occur
Solution Approach 1:
The patent extracts and removes synephrine from the composition while retaining other lipolytic-active compounds. The composition specifically excludes synephrine and other substances that may have adverse cardiovascular effects, thereby eliminating the harmful side effects while preserving the desired lipolytic activity through alternative natural compounds.
Solution Approach 2:
The patent creates a composite composition using multiple plant extracts (citrus fruits, guarana, mate, kola) that work synergistically to provide lipolytic activity. This composite approach replaces the single-substance synephrine with a multi-component natural mixture that achieves similar or enhanced fat burning effects without the harmful side effects.
2Power
If theophylline and caffeine are used for lipolytic activity, then fat burning effect is improved, but dietary balance is disrupted when consumed in excess
Solution Approach 1:
The patent carefully controls the concentration parameters of caffeine and other stimulants within specific ranges (caffeine: 0.1-4%, theophylline: 0.1-2%) to optimize lipolytic activity while maintaining dietary balance. By adjusting these compositional parameters, the invention achieves effective fat burning without excessive stimulant intake that would disrupt dietary balance.
Solution Approach 2:
The patent uses moderate, controlled amounts of caffeine and theophylline rather than high doses, achieving sufficient lipolytic activity through partial action. This approach avoids the excessive consumption that would lead to dietary imbalance while still providing effective fat burning support.
3Object-affected harmful factors
If natural plant extracts are used for lipolytic activity, then safety is improved, but effectiveness may be insufficient compared to synthetic compounds
Solution Approach 1:
The patent merges multiple natural plant extracts (citrus fruits containing polyphenols and flavonoids, guarana, mate, and kola) into a single composition. This combination synergistically enhances the lipolytic activity of individual components, achieving effectiveness comparable to or exceeding synthetic compounds while maintaining the safety advantages of natural origins.
Solution Approach 2:
The invention creates a composite natural material combining extracts from multiple plant species, each contributing different bioactive compounds that work together to enhance lipolytic activity. This composite natural formulation achieves high effectiveness without relying on synthetic compounds, thereby maintaining safety while improving potency.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively stimulates lipolysis, promoting fat burning and body mass loss without major side effects, as demonstrated by ex-vivo and in-vivo experiments, and is suitable for use as a food supplement or in food products.
Implementation Method 1
lipolysis leads to the burning of fat and can thus increase physical performance. Lipolysis is the biological phenomenon corresponding to the breakdown of fats by the body. Such degradation can in particular make it possible to release the energy stored in the form of fats in adipose tissue. At the physiological level, this degradation occurs in particular at the level of adipocyte cells, in the form of a reaction consisting of releasing fatty acids and glycerol by hydrolysis of triglycerides stored in said adipocyte cells.
Data Source
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AI summary
The invention relates to a composition having lipolytic activity that comprises at least polyphenols, especially in the form of flavonoids, in particular flavanones and anthocyanins, and phenolic acids, and caffeine. The invention also relates to a process for obtaining such a composition and the use of the composition for its administration with a view to promoting the burning of fats or promoting the loss of body mass.