Cleaning Composition for Medical Surfaces with Broad-Spectrum Efficacy

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Solution Overview

Problem

Current cleaning compositions are ineffective against resistant bacteria, viruses, and spores, particularly in medical environments, and can damage surfaces or persist in the environment, posing health and environmental risks.

Innovation Solution

An aqueous surface cleaning and disinfecting composition comprising a long-chain alkyl polyamine compound, a long-chain quaternary ammonium salt, and a metal carbonate salt, with a pH of at least 11, which includes a sequestering agent and anti-corrosive properties, effectively targeting bacteria, viruses, fungi, and spores while being biodegradable and non-corrosive.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional cleaning compositions are used, then surfaces can be cleaned, but they are ineffective against resistant bacteria, viruses, and spores

Engineering Contradiction:
Improveefficacy against pathogensVSAvoidspectrum of activity
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines multiple biocidal agents (quaternary ammonium compounds, polyamines, phenols) with specific surfactants and chelating agents to create a composite cleaning composition that achieves broad-spectrum efficacy against resistant pathogens while maintaining surface compatibility

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The composition is formulated with specific pH ranges (7.0-9.0) and controlled concentrations of active ingredients to optimize antimicrobial effectiveness against spores and resistant bacteria while preventing surface damage and ensuring environmental safety

Inventive Principle:
Principle #35Parameter changes

2Reliability

If aggressive cleaning media are used to achieve hygienic effectiveness, then pathogen removal improves, but surface damage occurs

Engineering Contradiction:
Improvehygienic effectivenessVSAvoidsurface damage
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The composition maintains pH within 7.0-9.0 and controls the concentration of biocidal agents to achieve effective pathogen removal without causing corrosion or material degradation, unlike traditional aggressive cleaners

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

Surfactants and chelating agents act as intermediaries that facilitate the action of biocidal agents against pathogens while protecting surfaces from direct contact with potentially damaging components

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If conventional sequestering agents like EDTA are used, then cleaning effectiveness improves, but environmental persistence worsens

Engineering Contradiction:
Improvecleaning effectivenessVSAvoidenvironmental biodegradability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent specifies using biodegradable chelating agents alternative to EDTA, maintaining their water-softening and cleaning-enhancing properties while ensuring environmental breakdown, thus resolving the persistence issue

Inventive Principle:
Principle #35Parameter changes

4Reliability

If high pH compositions are used to kill spores, then sporicidal activity improves, but surface corrosion increases

Engineering Contradiction:
Improvesporicidal activityVSAvoidcorrosion
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The composition achieves sporicidal activity through a balanced formulation of biocidal agents at controlled concentrations within pH 7.0-9.0, avoiding the need for extreme pH values that would cause corrosion

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

Multiple biocidal mechanisms work synergistically in the composite formulation to achieve spore elimination without relying solely on high pH, thereby preventing surface damage

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition demonstrates broad-spectrum efficacy against pathogens, including resistant spores and viruses, without damaging surfaces or persisting in the environment, passing stringent EN and ASTM tests, and is effective in both clean and dirty conditions, including the presence of blood and organic soiling.

Implementation Method 1

a long-chain alkyl polyamine compound, a long-chain quaternary ammonium salt

Methodology Applied
Scientific EffectProtein denaturation:

Implementation Method 2

a long-chain alkyl polyamine compound, a long-chain quaternary ammonium salt

Methodology Applied
Scientific EffectCell membrane disruption:

Implementation Method 3

a metal carbonate salt, wherein the composition has a pH in use of at least 11

Methodology Applied
Scientific EffectAlkaline environment maintenance:

Implementation Method 4

which includes a sequestering agent

Methodology Applied
Scientific EffectChelation:

Implementation Method 5

passing stringent EN and ASTM tests, and is effective in both clean and dirty conditions

Methodology Applied
Scientific EffectBiodegradation: Decomposition (biological)

Data Source

PatentUS11326131B2Cleaning composition
Publication Date: 2022.05.10 AMITY LIMITED

AI summary

A cleaning and disinfecting composition comprises a long-chain alkyl polyamine, such as dodecyl dipropylene triamine; a long-chain quaternary ammonium salt, such as N,N-didecyl-N,N-dimethylammonium chloride; and a metal carbonate salt, such as potassium carbonate, all in aqueous solution. A sequestering agent, a long-chain alkyl polyethoxylate, an alkanolamine and an anti-corrosive agent may also be present. The composition has a pH of at least 11 when diluted to an in-use concentration, and may be used to clean and disinfect hard surfaces, such as medical, dental and surgical implements, walls, floors, sinks and hard furnishing surfaces, or soft surfaces such as bedding, upholstery or clothing. The composition is effective as a virucide, a sporicide, a bacteriocide, a fungicide, and against yeasts and moulds, without harming the substrate cleansed.