Clinical Decision Support System with Probative Feature Detection

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Solution Overview

Problem

Conventional clinical decision support systems face challenges in distinguishing the significance of image features for similarity assessment and rely on manual or empirical methods, which can introduce bias and fail to capture subjective factors in medical diagnoses.

Innovation Solution

A clinical decision support system with a graphical user interface for manual grouping of patient cases and automated identification of probative features using machine learning, combining image and non-image features to provide accurate clinical decision support.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automated machine learning approaches are used to group similar cases, then productivity is improved, but measurement precision deteriorates due to the black box nature of the algorithm

Engineering Contradiction:
Improvecase grouping efficiencyVSAvoidsimilarity assessment accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system implements feedback by allowing physicians to review and correct automatically grouped cases. The physician interface enables manual adjustment of case groupings, and this feedback is used to refine and retrain the machine learning algorithm, improving its accuracy over time while maintaining automated efficiency.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system introduces an intermediary layer between automated grouping and final case similarity determination. The physician review interface acts as a mediator that can approve, modify, or reject algorithm-generated groupings, combining automated efficiency with human expertise to ensure measurement precision.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If manual pairwise comparison of image features is used to identify similar cases, then measurement precision is improved, but productivity deteriorates due to time-consuming manual assessment

Engineering Contradiction:
Improvefeature significance distinctionVSAvoidcase assessment speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system replaces manual mechanical comparison of image features with automated machine learning algorithms. The algorithm automatically extracts and compares image features, substituting the time-consuming manual process while maintaining the ability to distinguish feature significance through trained model parameters.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system performs preliminary automated grouping of cases based on image and non-image features before physician review. This preliminary action filters and organizes cases in advance, allowing physicians to focus their detailed manual assessment on fewer, more relevant cases, thereby improving overall productivity without sacrificing measurement precision.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If relevance feedback techniques are applied to refine information retrieval, then measurement precision is improved, but productivity deteriorates due to time required for feedback provision

Engineering Contradiction:
Improveretrieval accuracyVSAvoidfeedback provision speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system implements self-service by automatically generating relevance feedback signals from the structured case data and outcome information already present in the database. The algorithm learns from stored case outcomes and automatically refines its retrieval accuracy without requiring time-consuming manual feedback from physicians.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system performs preliminary refinement of case grouping algorithms using pre-collected outcome data from the database. By utilizing existing structured medical data and outcomes, the system proactively improves retrieval accuracy before clinical use, eliminating the need for real-time feedback provision during patient care.

Inventive Principle:
Principle #10Preliminary action

4Measurement precision

If comprehensive patient case data is stored and analyzed, then measurement precision is improved, but device complexity increases due to data management requirements

Engineering Contradiction:
Improvecase similarity determination accuracyVSAvoidsystem structure complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system segments patient case data into distinct categories including image features, non-image features, and outcome data. This segmentation allows the machine learning algorithm to process different data types separately and efficiently, managing complexity through modular data organization while maintaining comprehensive analysis for accurate case similarity determination.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS10504197B2Clinical decision support systems and methods
Publication Date: 2019.12.10 KONINKLIJKE PHILIPS NV
  • US10504197B2 patent drawing
  • US10504197B2 patent drawing
  • US10504197B2 patent drawing

AI summary

A clinical decision support (CDS) system comprises: a case grouping sub-system (10) including a graphical user interface (30) that is operative to simultaneously display data representing a plurality of patient cases and further configured to enable a user to group selected patient cases represented by the simultaneously displayed data into clinically related groups (32) as selected by the user; a probative features determination sub-system (12) that is operative to determine probative features (44) that correlate with the clinically related groups; and a CDS user interface (16) that is operative to receive current patient data relating to a current patient case and to output clinical decision support information based on values of the probative features determined from the received current patient data.