Closed Sampling Attachment for Contamination-Free Powder Transfer

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Solution Overview

Problem

Existing methods for sampling solids from manufacturing plants are not fully closed, leading to contamination risks, particulate issues, and unsuitable for products with poor flow properties, which can result in false-positive analytical results and product loss.

Innovation Solution

A method involving a walled container with a reinforcing element, where a fracture is made for a hollow tube insertion to transfer samples into a sealed container, ensuring a tight connection and minimizing contamination.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a sample is taken from a container using conventional methods, then the sample can be obtained, but the sample becomes contaminated with external substances and the original sample composition is altered

Engineering Contradiction:
Improvesample integrityVSAvoidcontamination
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The sampling device uses a nested structure where the sampling probe is inserted through a stopper into the sample container. The probe contains internal channels that are sealed during sampling to prevent contamination, and the stopper acts as a barrier between the external environment and the sample. This nesting approach allows the sampling system to be contained within the container while maintaining sample integrity.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The stopper serves as an intermediary element between the sampling device and the sample container. It provides a sealed interface that allows the sampling probe to access the sample without creating openings in the container wall, thus preventing contamination while enabling sample retrieval.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If the sample container is opened to retrieve a sample, then the sample can be accessed, but the container structure is compromised and contamination risk increases

Engineering Contradiction:
Improvesample accessVSAvoidcontainer integrity
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The sampling system is segmented into separate functional components: a stopper that can be inserted/removed from the container, and a sampling probe that can be inserted through the stopper. This segmentation allows the container to remain intact while providing access to the sample through the stopper-probe interface.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The stopper acts as an intermediary that maintains container integrity while enabling sample access. It provides a sealed interface that can be opened and closed without compromising the container structure, allowing repeated sampling operations.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If a stopper is inserted into the sample container to maintain integrity, then contamination is prevented, but the sampling process becomes more complex

Engineering Contradiction:
Improvesample integrityVSAvoidsampling procedure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The sampling probe and stopper are merged into a single integrated assembly that functions as one unit. The probe is inserted through the stopper as a single operation, and the combined structure provides both sampling capability and contamination prevention in one mechanism, reducing procedural complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The stopper-probe assembly serves multiple functions: it maintains container integrity, provides sample access, and enables contamination-free sampling. This multi-functionality reduces the need for separate components and procedures, simplifying the overall sampling process.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentEP3791150B1Method for closed sampling, and sampling device
Publication Date: 2026.05.06 BOEHRINGER INGELHEIM INT GMBH
  • EP3791150B1 patent drawingFigure 1a~1f
  • EP3791150B1 patent drawingFigure 2a~3
  • EP3791150B1 patent drawingFigure 4

AI summary

The invention relates to a method for closed sampling from filling systems, comprising the following steps: filling a container (1) comprising a wall (3) with a sample amount; applying a reinforcing element (20) to the container (1) comprising the wall; introducing a breakpoint (22) into the wall of the container (1) in the region of the reinforcing element (20); introducing a sampling attachment (30) with a hollow tube (40) into the wall of the container (1) in the region of the breakpoint (22); filling a sample container (50) connected to the hollow tube (40) once or multiple times; removing the sample container (50) from the hollow tube (40) and sealing the sample container (50); removing the sampling attachment (30) with the hollow tube (40) from the container; and sealing the breakpoint (22) of the container in the region of the reinforcing element (20). The invention also relates to a sampling device, in particular for carrying out the method.