Closure Membrane Taper for Reproducible Reagent Dosing
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Solution Overview
Problem
Existing photometric measurement methods are error-prone due to uncontrolled and non-reproducible destruction of the closure membrane in dosing containers, leading to inconsistent measurement results, especially when exact amounts of reagents and samples are required for medical tests.
Innovation Solution
A closure membrane with a predetermined breaking point, designed as a linearly extending material taper, is used, which breaks open in a defined manner when the filling pressure is exceeded, ensuring reproducible and precise dosing of reagents into the mixing container, and an integrated sampling system with a capillary for automatic sample volume measurement.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a closure membrane is used to seal the dosing container, then the reagent can be contained and dispensed, but the uncontrolled destruction of the membrane leads to non-reproducible measurement results
Solution Approach 1:
A predetermined breaking point is created in the closure membrane before use, allowing controlled rupture at a specific location when pressure is applied. This preliminary preparation ensures that the membrane fails in a predictable and reproducible manner during the dispensing process, eliminating the uncontrolled destruction that previously caused measurement errors.
Solution Approach 2:
The closure membrane is designed with a localized predetermined breaking point rather than uniform thickness. This local modification creates a specific weak point that will rupture first under pressure, ensuring controlled and reproducible membrane failure at a defined location, which prevents uncontrolled liquid escape and maintains measurement accuracy.
2Measurement precision
If exact amounts of sample and reagent are precisely prescribed, then measurement accuracy is improved, but the complexity of dosing and handling increases
Solution Approach 1:
The dosing container is pre-filled with the exact amount of reagent required for the test, and the closure membrane is pre-equipped with a predetermined breaking point. This preliminary preparation eliminates the need for complex dosing mechanisms during the test procedure, as the precise amount is already prepared and will be dispensed automatically when pressure is applied.
Solution Approach 2:
The system is designed to automatically dispense the correct amount of reagent through the predetermined breaking point mechanism, without requiring complex external dosing equipment or manual measurement. The structure itself provides the dosing function through its design, simplifying the overall system while maintaining precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach results in reproducible measurement results and eliminates the need for separate pipetting steps, providing high accuracy and cost savings by simplifying the test set production and user handling.
Implementation Method 1
the cavity having a has a closure piston that can be displaced axially into the cavity, which generates a predeterminable filling pressure in the reagent
Implementation Method 2
the predetermined breaking point of the closure membrane is designed as a linearly extending material taper of the closure membrane
Data Source
Figure 1
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AI summary
The invention relates to a test set (1) for a photometric measuring device, comprising a mixing container (2) which has a filling opening (3) and comprising a metering container (8) which can be sealingly inserted into the filling opening (3) of the mixing container (2) and which contains a liquid reagent (13) in a closed cavity (9). The cavity (9) has a closure plunger (11), which can be moved axially in the cavity (9), at a first end of the metering container (8), said closure plunger generating a specifiable filling pressure in the reagent (13), and the metering container (8) has a closure membrane (10) at a second metering container end which can be inserted into the mixing container (2). According to the invention, the closure membrane (10) is equipped with a predetermined breaking point (20) which breaks open when the filling pressure is exceeded in a defined manner as a result of an axial movement of the closure plunger (11), said predetermined breaking point (20) of the closure membrane (10) being formed as a linearly extending material taper of the closure membrane (10), wherein the taper is arranged eccentrically in the region of an opening (24) in the base (23) of the substantially cylindrical metering container (8).