CNN Blood Pressure Waveform Analysis for Hemodynamic Decompensation Prediction

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Solution Overview

Problem

It is challenging to determine when hemodynamic collapse is likely to occur in trauma patients due to the body's compensatory mechanisms maintaining vital signs despite blood loss, making it difficult to assess the risk of death from hemorrhage effectively.

Innovation Solution

A system using a trained convolutional neural network (CNN) processes blood pressure waveforms to estimate compensatory reserve and predict hemodynamic decompensation by analyzing physiological data, allowing for timely intervention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If compensatory mechanisms are active to maintain vital signs during blood loss, then patient stability is maintained, but the ability to detect impending hemodynamic collapse is reduced

Engineering Contradiction:
Improvepatient stabilityVSAvoiddifficulty to detect hemodynamic collapse
Core Design Contradiction:
ReliabilityVSDifficulty of detecting and measuring

Solution Approach 1:

The CNN model performs preliminary analysis of blood pressure waveform features to predict compensatory reserve levels before hemodynamic collapse occurs. By continuously monitoring and analyzing waveform characteristics in advance, the system detects subtle changes that indicate declining compensatory capacity, enabling early warning before vital signs deteriorate.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses blood pressure waveform features as an intermediary indicator to indirectly assess compensatory reserve. Instead of directly measuring compensatory mechanisms, the CNN analyzes intermediate waveform characteristics (such as amplitude, frequency, and morphology) that reflect the underlying physiological state, bridging the gap between stable vital signs and impending collapse.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Loss of time

If standard vital signs are monitored to assess patient status, then patient stability can be tracked, but early warning of hemodynamic decompensation is delayed

Engineering Contradiction:
Improvetime to detect decompensationVSAvoidprecision of hemodynamic status assessment
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The patent replaces traditional mechanical vital sign monitoring with an intelligent CNN-based analysis system. The neural network automatically extracts and analyzes complex waveform features, substituting manual or simple threshold-based monitoring with advanced pattern recognition that detects subtle changes in blood pressure waveforms indicative of declining compensatory reserve.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system monitors changes in waveform parameters (amplitude, frequency, morphology) rather than relying solely on traditional vital sign thresholds. By tracking parameter evolution over time and analyzing deviations from normal patterns, the CNN detects early signs of decompensation before standard vital signs show deterioration, reducing time loss while maintaining measurement precision.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20240374149A1Systems, Methods and Media for Estimating Compensatory Reserve and Predicting Hemodynamic Decompensation Using Physiological Data
Publication Date: 2024.11.14 UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SEC OF THE ARMY
  • US20240374149A1 patent drawing
  • US20240374149A1 patent drawing
  • US20240374149A1 patent drawing

AI summary

In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented.