CNN-Based 3D Medical Image Segmentation for Prostate Cancer Diagnosis

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Solution Overview

Problem

Current methods for analyzing medical images, particularly for prostate cancer diagnosis, rely heavily on radiologist interpretation and are limited in providing clear communication of results and treatment recommendations to patients, leading to potential misinterpretation and increased patient trauma due to lack of clarity in complex medical information.

Innovation Solution

The development of systems and methods for automated analysis of 3D medical images using convolutional neural networks (CNNs) to identify specific organs and tissue regions, such as the prostate, and determine radiopharmaceutical uptake metrics, enabling accurate assessment of prostate cancer severity and treatment efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automated analysis using CNNs is implemented, then productivity and diagnostic accuracy are improved, but device complexity increases

Engineering Contradiction:
Improveimage analysis speedVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent introduces a cloud-based processing server as an intermediary between the imaging device and the analysis system. The server hosts the CNN models and performs the complex computational tasks, allowing the local imaging device to remain relatively simple while still accessing advanced automated analysis capabilities through network connectivity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces manual radiologist interpretation with automated CNN-based image analysis. The neural networks automatically segment anatomical structures, identify pathologies, and generate diagnostic reports, substituting human cognitive processing with algorithmic analysis to improve productivity and consistency.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If radiologist interpretation is used, then diagnostic accuracy is maintained, but loss of time occurs due to manual analysis

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidanalysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent implements continuous automated analysis that processes images as they are acquired, eliminating the discontinuous workflow of manual review. The CNN models continuously analyze image data in real-time or near-real-time, providing immediate diagnostic support without the delays inherent in radiologist scheduling and manual interpretation.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent creates digital copies of radiologist expertise through trained CNN models. These neural networks are trained on large datasets of annotated medical images, effectively copying and encoding radiologist knowledge and diagnostic patterns into algorithms that can rapidly analyze new cases with consistent accuracy.

Inventive Principle:
Principle #26Copying

3Loss of information

If detailed radiologist reports are provided, then information completeness is improved, but object-generated harmful factors increase due to patient trauma from complex information

Engineering Contradiction:
Improveinformation completenessVSAvoidpatient trauma
Core Design Contradiction:
Loss of informationVSObject-generated harmful factors

Solution Approach 1:

The patent segments the diagnostic information into multiple hierarchical levels: detailed technical reports for physicians, simplified visual summaries for patients, and key finding highlights. This segmentation allows the same diagnostic data to be presented in appropriately complex formats for different audiences, maintaining information completeness while reducing patient trauma through simplified presentation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies different levels of information detail to different user groups. The system generates location-specific quality outputs: comprehensive technical details with full measurement precision for radiologists and physicians, but simplified, visually-oriented summaries with reduced technical complexity for patients. This local quality adaptation ensures each user receives information at the appropriate level of detail.

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS10973486B2Systems and methods for rapid neural network-based image segmentation and radiopharmaceutical uptake determination
Publication Date: 2021.04.13 EXINI DIAGNOSTICS
  • US10973486B2 patent drawing
  • US10973486B2 patent drawing
  • US10973486B2 patent drawing

AI summary

Presented herein are systems and methods that provide for automated analysis of three-dimensional (3D) medical images of a subject in order to automatically identify specific 3D volumes within the 3D images that correspond to specific organs and/or tissue. In certain embodiments, the accurate identification of one or more such volumes can be used to determine quantitative metrics that measure uptake of radiopharmaceuticals in particular organs and/or tissue regions. These uptake metrics can be used to assess disease state in a subject, determine a prognosis for a subject, and/or determine efficacy of a treatment modality.