Cochlear Implant Segmentation via Shape Library Models

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Solution Overview

Problem

Current methods for automatic segmentation of inner ear anatomy in post-implantation CT images are limited, as they require a pre-implantation CT and cannot accurately localize structures-of-interest (SOIs) without artifacts, especially for bilateral cochlear implant recipients without pre-implantation CT data.

Innovation Solution

The development of algorithms that enable automatic segmentation of SOIs in post-implantation CT images using a shape library-based approach, which coarsely segments the labyrinth, creates a target-specific active shape model, and refines the segmentation using eigenanalysis to minimize RMS distance, allowing for segmentation without pre-implantation CT data.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a pre-implantation CT is required for accurate segmentation, then segmentation accuracy is improved, but the applicability to bilateral cochlear implant recipients without pre-implantation CT data deteriorates

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidapplicability to bilateral CI recipients
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The method segments the inner ear anatomy into distinct components (labyrinth, scala tympani, scala vestibuli, spiral ganglion) using a multi-stage process. First, a shape library is created from training data, then a target-specific active shape model is constructed, and finally automatic segmentation is performed on post-implantation CT images. This segmentation approach enables accurate identification of anatomical structures without requiring pre-implantation CT data.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A shape library is created in advance from training CT images through manual segmentation and model construction. This pre-computed library of anatomical shapes serves as a reference for the automatic segmentation process, enabling the system to accurately segment structures in post-implantation CTs without needing the actual pre-implantation CT of the patient.

Inventive Principle:
Principle #10Preliminary action

2Ease of operation

If a shape library-based approach is used for automatic segmentation, then the need for pre-implantation CT is eliminated, but the complexity of the segmentation algorithm increases

Engineering Contradiction:
Improveease of use without pre-implantation CTVSAvoidalgorithm complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The method transforms the segmentation problem by changing parameters from direct image intensity analysis to shape-based modeling. A target-specific active shape model is constructed using eigenanalysis of the shape library, which captures the essential geometric variations of inner ear anatomy. This parameter transformation simplifies the segmentation process by reducing it to fitting pre-characterized shape models to the post-implantation CT data.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

A target-specific active shape model serves as an intermediary between the generic shape library and the patient-specific post-implantation CT images. This intermediate model is customized for each patient by selecting and combining shapes from the library that best match their anatomy, then used to guide the automatic segmentation process, bridging the gap between general anatomical knowledge and individual patient data.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If automatic segmentation is performed on post-implantation CT images with artifacts, then the localization accuracy of SOIs deteriorates, but the ability to process bilateral CI recipients without pre-implantation CT is improved

Engineering Contradiction:
Improveability to process bilateral CI recipientsVSAvoidlocalization accuracy of SOIs
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The method converts the presence of implant artifacts in post-implantation CT images from a hindrance into a workable condition. By using a shape library-based approach with pre-characterized anatomical models, the system can tolerate and compensate for artifacts that would otherwise prevent accurate segmentation. The shape constraints guide the segmentation algorithm to identify correct anatomical structures even when image quality is degraded by metallic artifacts from cochlear implants.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Data Source

PatentUS10102441B2Methods for automatic segmentation of inner ear anatomy in post-implantation CT and applications of same
Publication Date: 2018.10.16 VANDERBILT UNIV
  • US10102441B2 patent drawing
  • US10102441B2 patent drawing
  • US10102441B2 patent drawing

AI summary

A method for automatic segmentation of intra-cochlear anatomy in post-implantation CT image of bilateral cochlear implant recipients includes coarsely segmenting a labyrinth with a labyrinth surface chosen from a library of inner ear anatomy shapes; creating a target specific ASM for each of the labyrinth and the SOIs using a set of inner ear anatomy surfaces selected from the library of inner ear anatomy shapes such that the set of inner ear anatomy surfaces has the smallest dissimilarity quantity with the coarsely localized labyrinth surface in the post-implantation CT image; refining the coarsely segmented labyrinth surface by performing an ASM-based segmentation of the labyrinth using the target-specific ASM of the labyrinth to obtain a segmented labyrinth; and fitting the points of the target-specific ASM of the SOIs to their corresponding points on the segmented labyrinth to segment the SOIs in the post-implantation CT image.