Coffee Extract Composition for Postprandial Blood Sugar Control
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Solution Overview
Problem
Current methods are inadequate in effectively controlling postprandial blood sugar levels, which are crucial in preventing diabetes and its associated vascular complications.
Innovation Solution
A composition comprising a coffee extract as an active ingredient is used to suppress postprandial blood sugar rise. The coffee extract is obtained through a hot-water extraction process of roasted coffee beans, specifically those roasted at 200° C to 250° C for varying durations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional methods are used to control postprandial blood sugar, then some level of blood sugar management is achieved, but the control effectiveness is inadequate and vascular complications still occur
Solution Approach 1:
The patent changes the chemical parameter of the intervention by using coffee extract (containing chlorogenic acid and other polyphenols) instead of conventional pharmaceutical agents. This natural extract demonstrates superior ability to inhibit intestinal alpha-glucosidase and alpha-amylase, thereby more effectively controlling postprandial blood sugar rise and preventing vascular complications
Solution Approach 2:
The coffee extract acts as an intermediary substance that mediates between dietary carbohydrates and blood sugar levels. It inhibits the enzymatic breakdown of carbohydrates in the intestine, slowing glucose absorption and thereby controlling postprandial hyperglycemia without directly affecting insulin secretion or action
2Reliability
If therapeutic agents are administered to control postprandial hyperglycemia, then blood sugar levels improve, but the complexity of treatment increases
Solution Approach 1:
The patent employs coffee extract, a naturally available and inexpensive substance, as the therapeutic agent. This replaces complex pharmaceutical formulations with a simple, accessible natural product that can be easily incorporated into daily diet, thereby reducing treatment complexity while maintaining or improving effectiveness
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The coffee extract composition effectively inhibits the absorption of glucose in the small intestine, thereby reducing postprandial blood sugar levels and potentially aiding in the management of diabetes and prevention of vascular complications.
Implementation Method 1
The coffee extract composition effectively inhibits the absorption of glucose in the small intestine
Implementation Method 2
The coffee extract is obtained through a hot-water extraction process of roasted coffee beans
Data Source
AI summary
The present invention relates to a composition comprising a coffee hot-water extract as an active ingredient for suppressing the postprandial blood sugar rise, wherein the composition can effectively suppress the postprandial blood sugar rise by more strongly inhibiting α-glucosidase and α-amylase activities than typical coffee extracts to suppress the degradation and absorption of polysaccharides, disaccharides, and the like.