Roasted Coffee Bean Extract Fat Oxidation via Hydroxyhydroquinone Removal

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Solution Overview

Problem

Current methods for addressing obesity and metabolic syndrome, such as exercise, are difficult to maintain, and coffee drinks with high hydroxyhydroquinone levels do not adequately promote fat metabolism, highlighting the need for a substance that enhances fat oxidation and energy metabolism without requiring special training or excessive hydroxyhydroquinone.

Innovation Solution

A roasted coffee bean extract with reduced hydroxyhydroquinone content, containing chlorogenic acids or their salts, is used to enhance postprandial fat oxidation and energy metabolism, offering a convenient method to reduce the risk of obesity and metabolic syndrome.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If chlorogenic acid is used to enhance fat metabolism, then fat oxidation is promoted, but hydroxyhydroquinone generation causes unfavorable effects

Engineering Contradiction:
Improvefat oxidation rateVSAvoidhydroxyhydroquinone generation
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent applies extraction by removing hydroxyhydroquinone from the coffee extract through treatment with activated carbon or other adsorbents. This selectively eliminates the harmful component while preserving chlorogenic acid, resolving the contradiction between promoting fat oxidation and avoiding harmful byproduct generation.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent converts the harmful effect of hydroxyhydroquinone into a benefit by using it as a marker for purification. The removal process transforms a harmful substance into a quality control parameter, ensuring the final product has enhanced fat metabolism effects without unfavorable side effects.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

2Quantity of substance

If coffee drink contains high hydroxyhydroquinone, then chlorogenic acid content is high, but fat metabolism promotion is insufficient

Engineering Contradiction:
Improvechlorogenic acid contentVSAvoidfat metabolism promotion
Core Design Contradiction:
Quantity of substanceVSProductivity

Solution Approach 1:

The patent extracts only the beneficial chlorogenic acid component while removing hydroxyhydroquinone through adsorption processes. This creates a purified extract where the active ingredient is concentrated without the counteracting harmful substance, achieving superior fat metabolism promotion.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the compositional parameters of the coffee extract by controlling the hydroxyhydroquinone content to be less than 0.1% relative to chlorogenic acid. This parameter optimization ensures maximum fat metabolism promotion effectiveness.

Inventive Principle:
Principle #35Parameter changes

3Power

If exercise is performed to increase energy consumption, then metabolism is activated, but continual exercise is practically difficult

Engineering Contradiction:
Improveenergy consumptionVSAvoidexercise maintenance
Core Design Contradiction:
PowerVSEase of operation

Solution Approach 1:

The patent creates a self-service solution where the purified chlorogenic acid extract automatically activates metabolism and promotes fat oxidation without requiring external exercise input. The substance itself performs the metabolic activation function that would otherwise require physical activity.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent substitutes the mechanical exercise system with a chemical/biochemical system. Instead of using physical movement to activate metabolism, the purified chlorogenic acid extract directly stimulates metabolic pathways and fat oxidation through its biochemical activity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentEP2617429B1Fat oxidation or energy metabolism enhancer
Publication Date: 2015.01.07 KAO CORP
  • EP2617429B1 patent drawingFigure 1
  • EP2617429B1 patent drawingFigure 2
  • EP2617429B1 patent drawing

AI summary

A composition, a pharmaceutical product, a quasi-drug, a food, a drink, a pet food, a feed, and the like which are highly safe and have excellent facilitatory actions on fat oxidation or energy metabolism are provided. Also disclosed is a roasted coffee bean extract for use in enhancement of fat oxidation or energy metabolism, comprising chlorogenic acids or salts thereof and having the content of hydroxyhydroquinone of less than 0.1% by mass relative to the content of the chlorogenic acids. Further disclosed is use of a roasted coffee bean extract for the production of a fat oxidation or energy metabolism enhancer, comprising chlorogenic acids or salts thereof and having the content of hydroxyhydroquinone of less than 0.1% by mass relative to the content of the chlorogenic acids.