Coffee Fruit Polysaccharide Composition for Immune System Support

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Solution Overview

Problem

Current methods lack an effective polysaccharide composition for enhancing the immune system without adverse side effects, which is crucial for health maintenance and disease prevention.

Innovation Solution

A composition comprising at least 50% polysaccharides extracted from coffee fruit pulp, which can be administered in various forms, including powders, liquids, and capsules, to stimulate the immune system and promote overall health.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If polysaccharide composition is used to strengthen the immune system, then immune function is improved, but adverse side effects may occur

Engineering Contradiction:
Improveimmune functionVSAvoidadverse side effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by precisely controlling the polysaccharide composition parameters, specifically requiring at least 50% w/w polysaccharides with specific molecular weight ranges (10-1000 kDa), and controlling the ratio of different polysaccharide fractions. This parameter optimization ensures effective immune stimulation while minimizing adverse effects through standardized composition control.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite materials by creating a complex polysaccharide composition from coffee fruit pulp that contains multiple polysaccharide fractions with different molecular weights and structures. This composite approach, combining various polysaccharide types (arabinoxylans, arabinogalactans, pectins, celluloses, hemicelluloses) in specific proportions, enhances immune modulatory effects while reducing toxicity through synergistic interactions and balanced composition.

Inventive Principle:
Principle #40Composite materials

2Reliability

If coffee fruit pulp extract is concentrated to increase polysaccharide content, then immunostimulatory effect is enhanced, but extraction complexity increases

Engineering Contradiction:
Improveimmunostimulatory effectVSAvoidextraction process
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the extraction process into distinct stages: initial extraction to obtain total polysaccharides, followed by fractionation into different molecular weight ranges (10-1000 kDa, 100-500 kDa, etc.). This segmented approach allows control over the immunostimulatory active components while simplifying the overall process through systematic separation steps.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies the extraction principle by selectively isolating polysaccharides from coffee fruit pulp using aqueous extraction methods. The process extracts only the polysaccharide fraction (at least 50% w/w) while leaving behind other components, and further extracts specific molecular weight fractions that provide the desired immunostimulatory effects with simplified processing compared to whole extract methods.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS20240024401A1Polysaccharide composition and method for health maintenance and strengthening the immune system
Publication Date: 2024.01.25 PRASAD KODIMULE SHYAM
  • US20240024401A1 patent drawing
  • US20240024401A1 patent drawing
  • US20240024401A1 patent drawing

AI summary

The invention provides a polysaccharide-rich composition comprising coffee fruit extract. The composition produces an immunostimulatory effect and can increase the activity of macrophages. The composition finds use in methods of stimulating an immune response and supporting immune system function in a subject.