Cognitive Platform for Neurodegenerative Condition Detection

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Solution Overview

Problem

Current methods for detecting neurodegenerative conditions, such as Alzheimer's and Huntington's disease, are often invasive, expensive, and time-consuming, and may require massive equipment, making them impractical for widespread use.

Innovation Solution

A cognitive platform that uses a user interface, processing unit, and memory to assess cognitive skills by rendering primary and secondary tasks, with and without interference, and analyzing responses to generate a scoring output indicative of the likelihood of neurodegenerative condition onset or progression.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If physiological techniques are used to detect neurodegenerative conditions, then detection accuracy is improved, but equipment complexity and cost increase

Engineering Contradiction:
Improvedetection accuracyVSAvoidequipment complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces complex physiological measurement equipment with a cognitive platform that uses software-based cognitive tasks and interference paradigms. Instead of relying on expensive hardware for physiological measurements, the system uses computational tasks to assess cognitive domains (attention, memory, executive function) that are indicative of neurodegenerative conditions, thereby reducing equipment complexity while maintaining detection accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent creates a simplified copy of the assessment function that can be performed on standard computing devices. Rather than requiring specialized physiological measurement equipment, the system replicates the assessment capability through virtual cognitive tasks that can be executed on everyday computers, tablets, or smartphones, making the technology accessible without needing complex equipment.

Inventive Principle:
Principle #26Copying

2Measurement precision

If physiological techniques are used to detect neurodegenerative conditions, then detection accuracy is improved, but time consumption increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidtime consumption
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent implements continuous cognitive assessment through repeated trials of cognitive tasks with varying levels of interference. The system continuously measures performance across multiple domains (attention, memory, executive function) in an ongoing manner rather than through discrete, time-consuming physiological procedures. This continuous assessment approach maintains high detection accuracy while reducing the total time required compared to traditional physiological testing protocols.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent uses periodic presentation of cognitive tasks with different interference levels in a structured sequence. By systematically varying the interference conditions (low, medium, high) across multiple trials, the system efficiently gathers comprehensive cognitive data through repeated cycles of task performance, thereby achieving accurate detection in a time-efficient manner compared to continuous physiological monitoring.

Inventive Principle:
Principle #19Periodic action

3Measurement precision

If physiological techniques are used to detect neurodegenerative conditions, then detection accuracy is improved, but cost increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidcost
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent substitutes expensive physiological measurement equipment with software-based cognitive assessment tasks that can be executed on standard computing devices. By replacing hardware-dependent physiological techniques with computational cognitive tasks, the system dramatically reduces the cost barrier while maintaining the ability to detect neurodegenerative conditions through assessment of cognitive domains.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent creates an affordable copy of the assessment function that can be deployed on inexpensive computing platforms. Instead of requiring costly specialized equipment, the system replicates the detection capability through virtual cognitive tasks that can run on everyday devices, making the technology economically viable and accessible to a broader population.

Inventive Principle:
Principle #26Copying

4Measurement precision

If physiological techniques are used to detect neurodegenerative conditions, then detection accuracy is improved, but invasiveness increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidinvasiveness
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent replaces invasive physiological measurement techniques with non-invasive cognitive task performance assessment. Instead of physically measuring physiological parameters that may require bodily intrusion or uncomfortable procedures, the system assesses cognitive function through virtual tasks that evaluate attention, memory, and executive function, completely eliminating invasiveness while maintaining detection accuracy for neurodegenerative conditions.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent creates a non-invasive copy of the assessment function that evaluates cognitive domains through software-based tasks rather than physical physiological measurements. This virtual assessment approach replicates the detection capability without requiring any physical intrusion or uncomfortable procedures, making it completely non-invasive and suitable for routine screening.

Inventive Principle:
Principle #26Copying

Data Source

PatentUS12220242B2Cognitive platform configured as a biomarker or other type of marker
Publication Date: 2025.02.11 AKILI INTERACTIVE LABS INC
  • US12220242B2 patent drawing
  • US12220242B2 patent drawing
  • US12220242B2 patent drawing

AI summary

Example systems, methods, and apparatus are provided for using data collected from the responses of an individual with the computerized tasks of a cognitive platform to derive performance metrics as an indicator of cognitive abilities, and applying predictive models to generate an indication of a neurodegenerative condition. The example systems, methods, and apparatus also can be configured to adapt the computerized tasks to enhance the individual's cognitive abilities, and for using data collected from the responses of an individual with the adapted computerized tasks to derive performance metrics and applying predictive models to generate the indication of neurodegenerative condition.