Coiled Cannula for Single-Puncture Bone Marrow Disruption

Resolve Bottlenecks,
Find Innovative SolutionsGenerate Solutions

Solution Overview

Problem

Traditional bone marrow harvesting techniques require multiple punctures and are invasive, causing pain and risk of puncturing the cortical wall, while lacking flexibility and torque for efficient marrow extraction.

Innovation Solution

A flexible, rotatable aspiration cannula with a coiled shaft and stainless steel components, featuring a stiff proximal portion and flexible distal portion, allows for single-puncture entry and efficient marrow disruption and aspiration without puncturing the cortical wall.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If traditional bone marrow harvesting techniques are used with multiple punctures, then sufficient marrow can be harvested, but the procedure causes significant pain and risk of puncturing the cortical wall

Engineering Contradiction:

Improvemarrow harvestedVSAvoidpain and cortical wall puncture risk

Core Design Contradiction:

Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The cannula incorporates a flexible distal portion that can dynamically adapt its shape and orientation as it navigates through the cancellous bone, allowing it to follow the natural contours of the bone cavity and avoid the cortical wall while maintaining effective marrow contact for harvesting

Inventive Principle:

Principle #15Dynamics

Solution Approach 2:

The cannula features a flexible distal portion with a radius of curvature that allows it to bend and conform to the bone cavity geometry, preventing rigid penetration through the cortical wall while maintaining sufficient contact area for effective marrow aspiration

Inventive Principle:

Principle #30Flexible shells and thin films

2Adaptability or versatility

If the cannula is made flexible to maneuver around tortuous regions, then it can navigate the bone cavity, but it may lose torque transmission capability for tissue disruption

Engineering Contradiction:

Improvemaneuverability in bone cavityVSAvoidtorque transmission for tissue disruption

Core Design Contradiction:

Adaptability or versatilityVSForce

Solution Approach 1:

The cannula is divided into distinct segments with different mechanical properties: a stiff proximal portion for torque transmission and a flexible distal portion for navigation, allowing each segment to perform its specialized function optimally

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

Different portions of the cannula have locally optimized properties - the proximal portion maintains high stiffness for effective torque transmission to the disruption tip, while the distal portion has controlled flexibility for navigating tortuous bone pathways

Inventive Principle:

Principle #3Local quality

3Object-affected harmful factors

If a single puncture is used instead of multiple punctures, then pain and cortical wall damage are reduced, but the ability to harvest sufficient marrow is compromised

Engineering Contradiction:

Improvepain and cortical wall damageVSAvoidmarrow harvested

Core Design Contradiction:

Object-affected harmful factorsVSQuantity of substance

Solution Approach 1:

The flexible distal portion enables the cannula to explore the bone cavity in three dimensions, following the natural contours and extending into multiple regions through a single puncture site, effectively replacing the need for multiple puncture sites while maintaining comprehensive marrow harvesting

Inventive Principle:

Principle #17Another dimension (Dimensionality change)

Data Source

PatentEP3397172B1Cannula for tissue disruption

Publication Date: 2025.10.01 REGENMED SYSTEMS INC

Figure 1~2B
Figure 3
Figure 4A~4C

AI summary

A coiled shaft for tissue disruption is described herein where a flexible aspiration cannula has a first portion and a second portion formed of the coiled shaft. The cannula is configured in a particular embodiment to rotate over the length of the cannula to disrupt the matrix of bone marrow without the cannula buckling or collapsing. The cannula also includes a disruption tip coupled to the coiled shaft. The disruption tip has a radiused portion along a distal tip face of the disruption tip.