Coiled Aspiration Cannula Torque Transmission

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Solution Overview

Problem

Traditional bone marrow harvesting techniques are invasive, requiring multiple punctures and often result in donor discomfort, with a high risk of puncturing the cortical wall of the target bone, and are inefficient in terms of time and marrow collection.

Innovation Solution

A minimally invasive tissue disruption and aspiration device with a flexible, rotatable cannula that can be introduced through a single puncture opening, featuring a coiled structure for flexibility and torque transmission, preventing puncture of the cortical wall while effectively disrupting and aspirating bone marrow.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If traditional bone marrow harvesting techniques are used with multiple punctures, then sufficient bone marrow can be collected, but the risk of puncturing the cortical wall increases and donor discomfort increases

Engineering Contradiction:
Improvebone marrow collection volumeVSAvoidcortical wall puncture risk
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The cannula incorporates a flexible coiled structure that allows the device to navigate within the cancellous bone space without rigidly penetrating the cortical wall. The flexibility enables the cannula to conform to the bone cavity geometry, collecting marrow through multiple passages within the same puncture site rather than requiring multiple punctures through the cortical wall.

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The cannula is divided into distinct functional segments: a puncture tip for initial access, a flexible coiled body for navigation within the cancellous space, and a collection mechanism. This segmentation allows the device to perform multiple functions (puncture, navigate, collect) through a single puncture event, reducing cortical wall exposure.

Inventive Principle:
Principle #1Segmentation

2Quantity of substance

If traditional bone marrow harvesting techniques are used with multiple punctures, then sufficient bone marrow can be collected, but the procedure time increases

Engineering Contradiction:
Improvebone marrow collection volumeVSAvoidprocedure duration
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The cannula is pre-configured with an expanded coiled structure that is activated upon insertion into the cancellous bone. This preliminary configuration allows the device to immediately begin collecting marrow through multiple internal passages without requiring the surgeon to perform multiple separate puncture actions, thereby reducing procedure time while maintaining collection volume.

Inventive Principle:
Principle #10Preliminary action

3Quantity of substance

If traditional bone marrow harvesting techniques are used with multiple punctures, then sufficient bone marrow can be collected, but donor discomfort increases

Engineering Contradiction:
Improvebone marrow collection volumeVSAvoiddonor pain and discomfort
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The flexible coiled structure allows the cannula to navigate smoothly within the cancellous bone cavity without requiring repeated puncture actions. By confining the collection process to a single puncture site with multiple internal passages, the device significantly reduces the number of times the needle must penetrate skin and tissue, thereby reducing donor pain and discomfort while maintaining adequate marrow collection volume.

Inventive Principle:
Principle #30Flexible shells and thin films

4Reliability

If a flexible cannula structure is used to prevent cortical wall puncture, then safety improves, but torque transmission capability may be reduced

Engineering Contradiction:
Improvecortical wall puncture preventionVSAvoidtorque transmission
Core Design Contradiction:
ReliabilityVSForce

Solution Approach 1:

The cannula combines a rigid puncture tip segment for initial cortical wall penetration with a flexible coiled body segment for navigation within the cancellous space. The segmented design allows the rigid portion to provide necessary torque transmission during insertion while the flexible portion prevents unwanted cortical wall puncture during the collection phase, thus balancing torque requirements with safety.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device reduces the number of punctures needed, decreases procedure time, and minimizes the risk of cortical wall puncture, allowing for efficient bone marrow harvesting with reduced donor discomfort and improved safety.

Implementation Method 1

The cannula may be formed from a first portion which extends distally from a hub and a second portion which is joined to a distal end of the first portion along a transitional portion. The first portion may have a stiffness which is greater than a stiffness of the second portion so that the proximal portion of the cannula is able to provide structural stiffness to the cannula while the second portion is able to retain sufficient flexibility to maneuver within the bone cavity while retaining enough stiffness for torque transmission from the handle to the distally positioned aspirator tip.

Methodology Applied
Scientific EffectTorque transmission: Torque

Implementation Method 2

The tissue disruptor located at the distal end of the cannula may be configured to rotate about the longitudinal axis of the shaft and agitate or disrupt the contacted tissue from its surrounding tissue matrix to thus facilitate aspiration of the bone marrow.

Methodology Applied
Scientific EffectMechanical disruption: Mechanical Force

Implementation Method 3

a aspiration lumen that maintains fluid communication through the entire length of the cannula with the aspirator tip

Methodology Applied
Scientific EffectAspiration: Suction

Data Source

PatentUS20230309973A1Cannula for tissue disruption
Publication Date: 2023.10.05 REGENMED SYSTEMS INC
  • US20230309973A1 patent drawing
  • US20230309973A1 patent drawing
  • US20230309973A1 patent drawing

AI summary

A coiled shaft for tissue disruption is described herein where a flexible aspiration cannula has a first portion and a second portion formed of the coiled shaft. The cannula is configured in a particular embodiment to rotate over the length of the cannula to disrupt the matrix of bone marrow without the cannula buckling or collapsing. The cannula also includes a disruption tip coupled to the coiled shaft. The disruption tip has a radiused portion along a distal tip face of the disruption tip.