Coiled Collagen Carrier Packaging for Sterile Storage
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Solution Overview
Problem
Current methods for applying collagen carriers in minimally invasive surgery are hindered by the need for manual, dry rolling processes, which can lead to premature activation and instability of the collagen carriers, making them difficult to handle and apply effectively, especially when multiple applications are required quickly.
Innovation Solution
A packaging system for a form-stable coiled collagen carrier with a collagen layer and a coating layer comprising thrombin and fibrinogen, featuring a container with a compartment and a cover that allows easy removal and maintains sterility, along with a desiccant to prevent moisture absorption, ensuring the carrier remains stable and usable.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If manual dry rolling process is used to apply collagen carriers, then the carrier can be applied in minimally invasive surgery, but the carrier becomes difficult to handle and may spring open uncontrolled after insertion
Solution Approach 1:
The collagen carrier is pre-coiled into a stable configuration before use. The packaging system includes a pre-formed coiled carrier that maintains its shape, eliminating the need for manual rolling during surgery. This preliminary preparation ensures form stability while ease of application.
Solution Approach 2:
A packaging system with a specific cavity structure serves as an intermediary between storage and application. The cavity holds the coiled carrier in a stable position during storage and facilitates controlled removal and application, preventing premature activation while enabling easy handling.
2Productivity
If multiple collagen carriers need to be applied quickly in succession, then complete hemostasis can be achieved, but the same applicating member cannot be reused due to premature activation
Solution Approach 1:
The packaging system is designed to hold multiple individual coiled carriers separately in distinct cavities. Each carrier remains independently packaged and stable until application, allowing multiple carriers to be prepared and applied in quick succession without cross-contamination or premature activation.
Solution Approach 2:
The packaging cavity acts as an intermediary that maintains carrier stability during storage and transfer. The specific cavity design allows carriers to be removed one at a time while remaining stable, enabling rapid sequential application without requiring multiple applicating members.
3Ease of manufacture
If the collagen carrier is made flexible for manual rolling, then it can be bent and rolled up, but it becomes non-form-stable and difficult to manipulate after insertion
Solution Approach 1:
The carrier is pre-coiled into its final stable configuration during manufacturing rather than requiring manual rolling during surgery. The pre-formed coiled structure maintains flexibility for manufacturing while achieving form stability for surgical application, eliminating the need for surgeon manipulation.
Solution Approach 2:
The packaging system is designed as a disposable single-use item that includes the pre-coiled carrier. The carrier is manufactured in its final stable coiled form and disposed of after single use, eliminating the need for manual rolling and ensuring consistent form stability without requiring complex reusable applicating members.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The packaging system enables secure, sterile storage and easy application of form-stable coiled collagen carriers, preventing premature activation and ensuring stability, even when multiple applications are needed quickly, thus enhancing the efficiency of minimally invasive surgical procedures.
Implementation Method 1
along with a desiccant to prevent moisture absorption
Implementation Method 2
the components of the coating dissolve and partly diffuse into the wound surface. This is followed by the fibrinogen-thrombin reaction which initiates the last phase of physiological blood coagulation. Fibrinogen is converted into fibrin monomers which spontaneously polymerise to a fibrin clot
Data Source
Figure 1
Figure 2~3
Figure 4a~4b
AI summary
The present invention relates to a packaging for storing a form-stable coiled collagen carrier. The form-stable coiled collagen carrier comprises a collagen layer and a coating layer comprising thrombin and fibrinogen and having the shape of an elongated element with a number of windings of the collagen carrier about the longitudinal axis of the elongated element with at least one outer winding(s) being orientated so that the coating layer constitutes the outer surface of each of said outer winding(s). The packaging preferably comprises a container part having a compartment in which at least a part of the coiled collagen carrier is contained.