Coiled Blood Flow Modulator for Right Atrial Pressure Relief
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Solution Overview
Problem
Chronic kidney disease and heart failure patients experience elevated right atrium pressure, leading to inefficient diuresis and fluid overload, while heart valve diseases cause reduced blood flow efficiency and increased right atrial pressure, resulting in complications such as heart failure and damage to the heart muscle.
Innovation Solution
Implantable devices with a support frame and coiled wires or coilable flow occlusion strips that modulate blood flow by flexing between configurations to manage pressure, using active or passive mechanisms to regulate blood flow through vessels like the superior vena cava and inferior vena cava, reducing pressure and improving kidney perfusion.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If the coiled wire is made more flexible to allow greater configuration change, then the device can better modulate blood flow, but the structural stability may be compromised
Solution Approach 1:
The coiled wire is designed to be dynamically flexible, allowing it to change configuration in response to blood flow conditions while maintaining structural integrity through its coiled geometry and material properties
Solution Approach 2:
The coiled wire functions as a flexible structural element that can bend and deform to modulate blood flow, utilizing flexible material properties to achieve both adaptability and stability
2Reliability
If the device is designed to actively modulate blood flow to reduce pressure, then kidney function improves, but device complexity increases
Solution Approach 1:
The device utilizes the natural blood flow and pressure differential to automatically modulate flow through the coiled wire's configuration changes, eliminating the need for external power sources or complex control systems
Solution Approach 2:
The device replaces complex active mechanical control systems with a passive mechanical structure that responds to physiological conditions through elastic deformation and configuration changes
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The devices effectively reduce right atrium and vessel pressures, enhancing kidney function and reducing hospital readmissions by actively or passively managing blood flow, improving quality of life and survival rates.
Implementation Method 1
the coiled wire is adapted to flex between a collapsed configuration and an extended configuration
Data Source
AI summary
An implantable device may include a support frame and a coiled wire forming a coil stack, wherein the coiled wire has a first end and a second end, and is adapted to flex between a collapsed configuration and an extended configuration, and wherein the first end is coupled to or formed from the support frame and the second end is extendable and collapsible relative to the support frame. An implantable device may include a jacket surrounding at least a portion of the coiled wire. An implantable device may include a plurality of coiled wires forming a coil stack. An implantable device may include a coilable flow occlusion strip adapted to flex between a collapsed configuration and an extended configuration, and wherein the first end is coupled to the support frame and the second end is extendable and collapsible relative to the support frame.