Cold-Sterilizing Solution Using Segmented Hydrogen Peroxide and Glucose Pentaacetate
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Solution Overview
Problem
Current sterilization methods for non-disposable materials are inadequate due to incompatibility with thermolabile devices, generation of hazardous substances, and stability issues of peracetic acid solutions, which also produce unpleasant odors and residues.
Innovation Solution
A disinfecting and sterilizing composition comprising hydrogen peroxide and glucose pentaacetate, with a solvent selected from acetone, esters, or dimethyl carbonate, that maintains stability and neutrality, avoiding aggressive pH and odor issues, and is stored in separate compartments for on-demand mixing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stability of the object's composition
If peracetic acid solutions are kept at pH below 4 to maintain stability, then solution stability is improved, but corrosiveness to materials and danger to operators increases
Solution Approach 1:
The invention divides the peracetic acid solution into two separate stable components: a peroxide solution (containing hydrogen peroxide or organic peroxides) and an acetylating agent solution (containing acetylacetone, acetylacetone hydrate, or other acetylating agents). These components are stored separately and only mix upon application to the surface, allowing each component to be stored stably without requiring acidic pH conditions that would cause corrosion.
Solution Approach 2:
The invention pre-prepares stable storage solutions of peroxide and acetylating agents separately, which can be stored indefinitely without degradation. When applied together, they rapidly generate peracetic acid in situ on the surface to be sterilized, eliminating the need to store corrosive acidic peracetic acid solutions long-term.
2Reliability
If peracetic acid is generated by mixing concentrated components, then disinfecting effectiveness is improved, but pungent odor and unpleasantness for operators increases
Solution Approach 1:
The invention uses specific parameter changes in the form of selecting particular chemical compounds with lower odor characteristics. Instead of using traditional peracetic acid formulations that produce strong pungent odors, the invention employs peroxide combined with acetylating agents that generate peracetic acid in situ with reduced odor emission, while maintaining effective disinfecting concentrations.
3Object-affected harmful factors
If peracetic acid solutions are prepared extemporaneously to avoid stability problems, then compatibility with materials is improved, but preparation time and operational complexity increases
Solution Approach 1:
The invention segments the peracetic acid generation system into two pre-mixed, pre-labeled component bottles that can be stored separately. Each component is ready for immediate use and simply needs to be mixed in the correct proportions when applied to the surface, eliminating the need for extemporaneous preparation while maintaining material compatibility.
Solution Approach 2:
The invention designs the system so that the peroxide and acetylating agent components automatically mix and react when applied together, self-generating the active peracetic acid sterilizing agent on-demand. This eliminates the need for complex preparation procedures while ensuring consistent, reliable sterilization effectiveness.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution provides a stable, non-aggressive, and effective cold-sterilizing agent with reduced toxicity and odor, ensuring compatibility with various materials, maintaining stability, and offering flexibility in use and disposal, while reducing logistical costs and environmental risks.
Implementation Method 1
a disinfecting and cold-sterilizing composition having a buffered pH comprised between 4 and 8, and comprising at least two components, wherein the first component comprises hydrogen peroxide and the second component comprises glucose pentaacetate
Implementation Method 2
the second component comprises glucose pentaacetate and a solvent selected from the group consisting of acetone, an ester of a mono- or poly- carboxylic organic acid, dimethyl carbonate and mixtures thereof
Data Source
AI summary
A disinfecting and cold-sterilizing solution, comprising a first hydrogen peroxide component and a second component comprising glucose pentaacetate. The two components are mixed at the time of use, so as to generate a solution that has a high disinfecting power and is suitable for the cold treatment of surgical instruments that cannot be sterilized by heat.