Collagen Hydrolysate and Rosehip Composition for Joint Repair

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Solution Overview

Problem

Current treatments for degenerative joint diseases, such as osteoarthritis, have limitations in effectively stimulating the biosynthesis of cartilage components, and existing compositions may not adequately address inflammation and cartilage wear.

Innovation Solution

A composition combining collagen hydrolyzate and rosehip powder or extract, with a specific weight ratio of 10:1 to 20:1, which enhances the biosynthesis of collagen and proteoglycans through a synergistic effect, addressing inflammation and promoting cartilage repair.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If collagen hydrolyzate is used to treat degenerative joint diseases, then cartilage protection and biosynthesis stimulation are improved, but anti-inflammatory effect is insufficient

Engineering Contradiction:
Improvecartilage protectionVSAvoidinflammation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent combines collagen hydrolyzate with rosehip extract in a specific composition, merging the cartilage-protective effects of collagen with the anti-inflammatory properties of rosehip. This combination allows the treatment to simultaneously address both cartilage degradation and inflammation, resolving the contradiction between improving cartilage protection and reducing harmful inflammatory effects.

Inventive Principle:
Principle #5Merging (Combining)

2Object-affected harmful factors

If rosehip extract is used alone for anti-inflammatory treatment, then inflammation is reduced, but cartilage biosynthesis stimulation is insufficient

Engineering Contradiction:
ImproveinflammationVSAvoidcartilage biosynthesis
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent merges rosehip extract with collagen hydrolyzate in a specific composition, combining the anti-inflammatory effects of rosehip with the cartilage biosynthesis stimulation of collagen. This allows the treatment to simultaneously reduce inflammation and promote cartilage repair, resolving the contradiction between reducing harmful inflammatory effects and improving cartilage biosynthesis.

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If high concentration of rosehip extract is used to enhance biosynthesis, then biosynthesis stimulation is improved, but cost and complexity increase

Engineering Contradiction:
Improvebiosynthesis stimulationVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent optimizes the concentration parameters of both collagen hydrolyzate and rosehip extract in the composition, finding a specific weight ratio range that achieves effective biosynthesis stimulation without excessive complexity. By carefully controlling the concentration parameters within defined ranges, the patent resolves the contradiction between achieving sufficient biosynthesis stimulation and maintaining reasonable composition simplicity.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination significantly increases collagen and proteoglycan biosynthesis, providing enhanced pain relief and cartilage protection, making it an effective treatment for degenerative joint diseases.

Implementation Method 1

the stimulating effect of collagen hydrolyzate on the biosynthesis of collagen and proteoglycans in the chondrocytes can be enhanced by a combination with rosehip powder or extract

Methodology Applied
Scientific EffectBiosynthesis:

Data Source

PatentEP2445510B1Compositions for treating degenerative joint diseases
Publication Date: 2017.12.27 GELITA AG
  • EP2445510B1 patent drawingFigure 1~2
  • EP2445510B1 patent drawingFigure 3~4
  • EP2445510B1 patent drawingFigure 5~6

AI summary

The invention relates to a composition for treating degenerative joint diseases having improved effectivity, wherein the composition comprises collagen hydrolysate and rosehip powder and/or extract, wherein the weight ratio of collagen hydrolysate to rosehip powder and/or extract, based on dry weight, is in the range from approximately 2:1 to approximately 100:1.