Collapsible Spacer for MDI Inhalation Devices

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Solution Overview

Problem

Conventional inhalation devices using pressurized aerosol canisters are not effective for many patients, as they do not facilitate optimal inhalation of medications for tracheal, bronchial, nasal, and pulmonary conditions, leading to inefficient medication distribution.

Innovation Solution

A collapsible inhalation device with a tubular, pliable sleeve member and end members that form a chamber to mix medication with air, featuring one-way valves and a blowback relief valve, encouraging slow inhalation by using negative thoracic pressure to prevent rapid inhalation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If direct use of pressurized aerosol canisters is used to deliver medication, then the device is simple and portable, but the medication distribution is inefficient and patients do not obtain optimum benefits

Engineering Contradiction:
Improveease of useVSAvoidmedication delivery effectiveness
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent introduces a spacer chamber as an intermediary device between the pressurized aerosol canister and the patient's mouth. This spacer receives the pressurized medication dose and allows it to mix with ambient air, converting the concentrated pressurized form into a nonpressurized, diluted form that can be inhaled more effectively. The spacer acts as a mediator that transforms the medication delivery mechanism to improve patient uptake while maintaining the simplicity of the original canister system.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If an expandable breathing bag or spacer is provided to promote long and slow inspiration, then medication distribution improves, but the device complexity increases

Engineering Contradiction:
Improvemedication distribution efficiencyVSAvoiddevice structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent employs a flexible, collapsible bag made of thin film material as the spacer chamber. This flexible shell allows the chamber to expand when receiving the pressurized medication dose and collapse during the inhalation process, providing the necessary volume changes to promote slow inhalation without requiring complex mechanical structures. The thin film construction keeps the device simple and lightweight while achieving the desired respiratory control function.

Inventive Principle:
Principle #30Flexible shells and thin films

3Volume of moving object

If the sleeve member is made collapsible to reduce storage size, then portability improves, but the manufacturing precision requirements increase

Engineering Contradiction:
Improvestorage volumeVSAvoidsealing and engagement precision
Core Design Contradiction:
Volume of moving objectVSManufacturing precision

Solution Approach 1:

The collapsible sleeve is constructed from flexible thin film material that can be folded or collapsed into a compact form for storage and transport. The flexibility of the thin film allows it to conform to the engagement features of the end members, providing effective sealing through deformation rather than requiring precision-machined sealing surfaces. This approach reduces storage volume while maintaining manufacturing feasibility through the use of formable thin material.

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device effectively converts concentrated medication from aerosol canisters into a nonpressurized form, promoting efficient and effective inhalation by ensuring medication is inhaled slowly and uniformly, enhancing treatment efficacy for respiratory conditions.

Implementation Method 1

the patient is required during respiratory maneuvers to utilize a negative thoracic pressure upon inhalation

Methodology Applied
Scientific EffectNegative thoracic pressure: Pressure Gradient

Implementation Method 2

a dose of the medication can be dispensed from the MDI dispenser into the chamber through the inlet port to mix with air in the chamber and thereby form a mixture of the air and the dose of the medication

Methodology Applied
Scientific EffectMixing:

Data Source

PatentUS10245396B2Inhalation devices and systems and methods including the same
Publication Date: 2019.04.02 AVALO THERAPEUTICS INC
  • US10245396B2 patent drawing
  • US10245396B2 patent drawing
  • US10245396B2 patent drawing

AI summary

A collapsible inhalation device for use with a metered dose inhaler (MDI) dispenser includes an outlet end member, an inlet end member and a tubular, pliable, collapsible sleeve member attached at either end to the inlet and outlet members. The outlet end member includes a mouthpiece. The inlet end member includes an inlet port and an MDI dispenser mount structure configured to receive and engage the MDI dispenser. The inhalation device is positionable in each of an open position, wherein the sleeve member defines a chamber, and a closed position, wherein the sleeve member is collapsed and enveloped by the outlet end member and the inlet end member.