Collimated Line Source Calibration for Low-Exposure SPECT Imaging

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Solution Overview

Problem

Nuclear medicine imaging systems, particularly SPECT systems, face inefficiencies in calibration due to the need for extensive statistical data collection, which leads to prolonged downtime, radiation exposure risks, and scheduling delays, and results in inaccurate image corrections and non-uniform images.

Innovation Solution

A collimated line source of radiation is used for calibration, aligned along a central axis with collimator plates to absorb photons in non-perpendicular directions, reducing radiation exposure and allowing piecemeal data collection during patient examination intervals.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional calibration methods using uncollimated radioactive sources are used, then calibration data can be collected, but radiation exposure to personnel and patients increases significantly

Engineering Contradiction:
Improvecalibration data qualityVSAvoidradiation exposure
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The collimator introduces spatial selectivity, allowing photons to be detected only from specific directional regions. This creates local quality in radiation detection by restricting the detection field to only those photons traveling along the optical axis, thereby reducing overall radiation exposure while maintaining calibration data quality

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The collimator acts as an intermediary component between the radioactive source and detector. It mediates the interaction by selectively transmitting photons based on their direction, allowing calibration to proceed with reduced radiation exposure by blocking photons that would otherwise contribute to exposure but not to useful calibration signals

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If extensive calibration data collection is performed to ensure accuracy, then calibration precision improves, but system downtime increases

Engineering Contradiction:
Improvecalibration accuracyVSAvoidsystem downtime
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The collimator is pre-configured with the radioactive source in a controlled manner before calibration begins. This preliminary arrangement ensures that photons are emitted and detected in a highly efficient geometric configuration, allowing sufficient calibration data to be collected in shorter time periods without compromising accuracy

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The collimator changes the spatial distribution parameter of photon detection by restricting acceptance to narrow angular ranges. This parameter change concentrates detection efficiency, allowing the system to accumulate sufficient statistical data for accurate calibration more rapidly than with uncollimated sources

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If calibration is performed frequently to maintain accuracy, then image quality improves, but scheduling efficiency decreases

Engineering Contradiction:
Improveimage qualityVSAvoidscheduling efficiency
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The collimated calibration system enables quicker calibration cycles, allowing the SPECT system to return to patient examinations more rapidly. This maintains continuous productive operation, improving scheduling efficiency while still performing calibration frequently enough to maintain image quality standards

Inventive Principle:
Principle #20Continuity of useful action

4Object-affected harmful factors

If a weaker calibration source is used to reduce radiation exposure, then safety improves, but calibration data collection time increases

Engineering Contradiction:
Improveradiation exposureVSAvoidcalibration time
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The collimator creates an asymmetric detection geometry where photons are accepted from a highly restricted directional range. This asymmetric configuration concentrates the detection efficiency along the optical axis, compensating for the reduced source strength by maximizing the utilization of photons that do reach the detector

Inventive Principle:
Principle #4Asymmetry

Solution Approach 2:

The collimator changes the angular distribution parameter of photon detection, creating a narrow acceptance cone. This parameter change increases the efficiency of photon utilization from the weak source, allowing sufficient calibration data to be collected even with reduced radiation exposure

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances SPECT system availability and efficiency by minimizing radiation exposure and reducing calibration time, enabling more frequent data collection without system downtime, thus improving image quality and patient throughput.

Implementation Method 1

a plurality of collimator plates arranged perpendicularly around the central axis, the collimator plates including a material with an atomic number and a density to substantially absorb photons striking the collimator plates

Methodology Applied
Scientific EffectPhotoelectric absorption: Absorption (EM radiation)

Implementation Method 2

A collimated line source of radiation for calibrating a single photon emission computed tomography (SPECT) imaging system, the collimated line source comprising a radioactive material aligned along a central axis

Methodology Applied
Scientific EffectRadioactive decay: Radioactive Decay

Data Source

PatentUS12611148B2Systems and methods for SPECT detector calibration
Publication Date: 2026.04.28 GE PRECISION HEALTHCARE LLC
  • US12611148B2 patent drawing
  • US12611148B2 patent drawing
  • US12611148B2 patent drawing

AI summary

Methods and systems are provided for calibrating a single photon emission computed tomography (SPECT) imaging system. In one example, a collimated line source for calibrating a SPECT system comprises a radioactive material aligned along a central axis of the collimated line source and a plurality of collimator plates arranged perpendicularly around the central axis, the collimator plates including a material that substantially absorbs photons striking the collimator plates. The collimator plates may absorb photons emitted by the radioactive material in non-perpendicular directions, which are not used for calibrating the SPECT imaging system, thereby reducing an amount of radiation released in an environment of the SPECT imaging system during calibration. Due to the reduced amount of radiation to which people in the environment are exposed, short time increments between patient examinations may be advantageously used to collect calibration data, reducing an overall amount of time used for calibration.