Colon Segmentation via Multi-Tiered Information Propagation

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Solution Overview

Problem

Current computer-aided diagnosis systems for virtual colonography face challenges in accurately segmenting the colon due to its highly variable topology, presence of Haustral folds, and overlapping intensity regions, leading to inaccurate and complex segmentation methods that are resource-intensive.

Innovation Solution

A multi-tiered information propagation framework using statistical and variational methods, including initial segmentation, 3D global convexification minimization, and post-processing techniques like connected component analysis and morphological operations, to enhance the accuracy and efficiency of colon segmentation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Extent of automation

If automated region growing and tissue classification methods are used for colon segmentation, then segmentation can be performed without manual intervention, but accuracy deteriorates due to the colon's highly variable topology and overlapping intensity regions

Engineering Contradiction:
Improveautomation of segmentationVSAvoidsegmentation accuracy
Core Design Contradiction:
Extent of automationVSMeasurement precision

Solution Approach 1:

The method segments the colon into multiple topological components by detecting haustral folds and dividing the colon into segments based on these folds. This segmentation allows each region to be processed independently, improving accuracy by accounting for the colon's variable topology while maintaining automation through algorithmic detection of fold patterns.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent transitions from 2D image processing to 3D volumetric analysis by creating a 3D representation of the colon from CT scan data. This dimensional change enables the system to capture the colon's three-dimensional topology and haustral folds, significantly improving segmentation accuracy while maintaining automated processing through 3D algorithmic analysis.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If complex segmentation algorithms are used to handle the colon's variable topology, then segmentation accuracy may improve, but computational complexity and resource requirements increase

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidalgorithmic complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The method performs preliminary actions by first detecting haustral folds and creating a 3D representation of the colon before performing the actual segmentation. This preliminary processing simplifies the subsequent segmentation task by pre-organizing the data structure, reducing the complexity of the main algorithm while maintaining high accuracy through the pre-computed topological information.

Inventive Principle:
Principle #10Preliminary action

3Productivity

If traditional segmentation methods are used, then processing can be completed, but computational time and memory requirements are excessive

Engineering Contradiction:
Improveprocessing speedVSAvoidcomputational resource consumption
Core Design Contradiction:
ProductivityVSUse of energy by stationary object

Solution Approach 1:

By segmenting the colon into discrete topological components based on haustral folds, the algorithm reduces the computational burden by processing smaller, manageable regions rather than the entire colon volume at once. This segmentation strategy decreases memory requirements and processing time while maintaining segmentation accuracy through the preserved topological relationships between segments.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS10242444B1Segmentation of the colon for accurate virtual navigation
Publication Date: 2019.03.26 KENTUCKY IMAGING TECH LLC
  • US10242444B1 patent drawing
  • US10242444B1 patent drawing
  • US10242444B1 patent drawing

AI summary

The present development is a method for generating a computer-aided accurate segmentation of an irregular structure, such as a colon The approach is based on a multi-tiered information propagation framework using statistical and variational methods. First, an initial segmentation using a method such as intensity based or shape-model registration for a volume of a typical CT is generated. The segmented image is subjected to a global/convex continuous minimization approach. After minimization, the data goes through post processing, and then the final segmented irregular structure output volume is generated.