Colorimetric Sensor Patch for Quantitative Perspiration Analysis
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Solution Overview
Problem
Current methods for measuring perspiration in controlled laboratory settings are not suitable for real-world applications, as they lack portability and efficiency in quantitatively determining perspiration volume, rate, and biochemical components.
Innovation Solution
A sensor patch with a perspiration volume sensing channel and biochemical component sensing chambers, integrated with a near-field communication (NFC) circuit, which changes color in response to perspiration and biochemical components, and can be analyzed using a smart device to determine these parameters.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional chemical analysis techniques are used in controlled laboratory environments, then measurement precision is improved, but device complexity and portability are worsened
Solution Approach 1:
The system is divided into two functional segments: a portable sensor patch that collects and preliminarily processes perspiration samples, and a separate analysis component that can be either a simplified on-device analyzer or a laboratory instrument. This segmentation allows the complex analysis functions to be isolated while maintaining portability and ease of use in the sensor patch itself.
Solution Approach 2:
The patent introduces intermediate reagents and colorimetric indicators as mediators between the perspiration sample and the detection system. These intermediaries enable quantitative measurement of perspiration components through color changes that can be detected by simple optical sensors, bridging the gap between complex biochemical analysis and simple detection mechanisms.
2Measurement precision
If conventional laboratory methods are used, then measurement accuracy is improved, but ease of operation and real-time analysis capability are worsened
Solution Approach 1:
The sensor patch is designed to be self-contained and self-operating. It automatically collects perspiration through capillary action, performs preliminary processing of the sample, and generates measurable signals without requiring user intervention for sample preparation or handling. The patch adheres to the skin and functions autonomously, eliminating complex operational steps.
Solution Approach 2:
The patent replaces manual mechanical operations (such as manual sample collection, transfer, and preparation) with automated capillary-driven fluid transport and integrated microstructures. The perspiration sample moves through the patch automatically via capillary forces, eliminating the need for syringes, pipettes, or other manual handling equipment.
3Measurement precision
If quantitative measurement of perspiration volume and rate is implemented, then measurement capability is improved, but device complexity is worsened
Solution Approach 1:
The patent employs colorimetric materials that undergo quantifiable color changes in response to perspiration volume and biochemical components. The intensity and progression of color changes provide information about perspiration rate and volume, enabling quantitative measurement through simple optical detection rather than complex volumetric or flow measurement mechanisms.
Solution Approach 2:
The sensor patch is designed to collect and process perspiration in periodic cycles, with the colorimetric reaction progressing over time in a predictable manner. By measuring color changes at specific time intervals or tracking the progression of the color front through the patch, the system can calculate perspiration rate and volume without requiring continuous complex monitoring.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables quantitative measurement of perspiration volume, rate, and biochemical components like sodium ions, chloride ions, glucose, and lactate, providing a non-invasive, portable, and efficient method for real-time analysis.
Implementation Method 1
The channel can include at least a first colorimetric material that changes color in response to exposure to perspiration
Implementation Method 2
The chamber can include at least a second colorimetric material that changes color in response to exposure to a biochemical component in the perspiration
Data Source
AI summary
A perspiration sensing system includes a sensor patch and a smart device. The sensor patch includes one or more perspiration sensing portions. The one or more perspiration sensing portions include an inlet having a predefined size to receive perspiration from a predefined number of sweat glands and an outlet for reducing back pressure. At least one perspiration sensing portion includes a channel having a colorimetric sensing material that changes color when exposed to perspiration. At least one perspiration sensing portion includes a colorimetric assay in a substrate that changes color when exposed to biochemical components of perspiration. The system further includes a smart device having a camera that can take a picture of the sensor patch and determine the volume, rate of perspiration, and/or biochemical components of the perspiration from the one or more perspiration sensing portions.