Compact Water Purification and Medicament Proportioning for Home Dialysate

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Solution Overview

Problem

Current systems for preparing medicaments, such as dialysate, in home settings lack the safety and precision required for effective medical treatments due to the need for large reverse osmosis plants, which are impractical and require high maintenance, and there is a need for innovative solutions to provide purified water and precisely mixed medicaments in a compact and reliable form.

Innovation Solution

A compact system integrating a water purification module and a medicament proportioning module that uses replaceable tagged components with data carriers for precise control and safety, allowing for on-demand purification and mixing of medicaments, reducing the need for large infrastructure and complex maintenance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If large reverse osmosis plants are used to provide purified water in home settings, then water purification quality is improved, but system size and infrastructure requirements worsen

Engineering Contradiction:
Improvewater purification qualityVSAvoidsystem size
Core Design Contradiction:
ReliabilityVSVolume of stationary object

Solution Approach 1:

The water purification system is divided into multiple smaller filtration stages (reverse osmosis membrane, ultrafiltration membrane, activated carbon filters) that can be arranged in series. Each stage handles a specific aspect of purification, allowing the system to achieve high purification quality without requiring a single large processing unit, thus reducing overall system footprint for home use

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs nested filtration where smaller filtration elements are contained within larger housing structures. The reverse osmosis membrane is housed within a pressure vessel that is integrated into the larger purification system. This nested arrangement maximizes the use of space and allows compact configuration of multiple filtration stages in a space-efficient manner

Inventive Principle:
Principle #7Nested doll (Nesting)

2Reliability

If complex treatment systems are implemented to ensure patient safety and treatment efficacy, then treatment reliability is improved, but system complexity and maintenance requirements worsen

Engineering Contradiction:
Improvetreatment safetyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system incorporates multiple sensors that continuously monitor treatment parameters (pressure, temperature, flow rate, conductivity) and provide feedback to the control unit. This automated feedback mechanism ensures patient safety by detecting anomalies and adjusting operations in real-time, while reducing the need for complex manual monitoring systems and simplifying maintenance through automated diagnostics

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The control unit automatically manages system operations based on sensor feedback, performing self-diagnosis and self-adjustment to maintain safe treatment conditions. This automation reduces the complexity of operator intervention required while maintaining high reliability through consistent automated safety checks and protocol enforcement

Inventive Principle:
Principle #25Self-service

3Manufacturing precision

If precise proportioning systems are used to mix medicaments with accurate solute concentrations, then medicament mixing precision is improved, but device complexity and training requirements worsen

Engineering Contradiction:
Improvemedicament mixing precisionVSAvoidproportioning system complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The system replaces manual proportioning operations with automated electronic control. Flow meters and pumps are controlled by a microprocessor-based control unit that calculates and adjusts flow rates to achieve precise medicament concentrations. This substitution of mechanical manual operations with automated electronic systems maintains high mixing precision while reducing the complexity of user interaction and training requirements

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Productivity

If continuous proportioning systems are deployed for medicament preparation, then medicament production efficiency is improved, but water consumption and drainage requirements worsen

Engineering Contradiction:
Improvemedicament production efficiencyVSAvoidwater consumption
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The system maintains continuous operation of the reverse osmosis and ultrafiltration membranes during medicament preparation, ensuring that purified water is continuously available for mixing. This continuous operation eliminates the need for batch processing and repeated purification cycles, improving medicament production efficiency while optimizing water usage through sustained membrane operation at steady state

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The system recovers and reuses purified water that contacts the medicament concentrate but does not undergo complete dialysis. This recovered water is redirected back into the purification stream or used for non-critical dilution purposes, reducing overall water consumption while maintaining continuous medicament production capability

Inventive Principle:
Principle #34Discarding and recovering

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides a safe, reliable, and compact solution for preparing purified water and medicaments, ensuring precise mixing and minimizing maintenance, suitable for home or critical care environments without the need for high-capacity water supply or drainage systems.

Implementation Method 1

In clinics, large reverse osmosis plants provide a continuous supply of purified water.

Methodology Applied
Scientific EffectReverse osmosis: Reverse Osmosis

Implementation Method 2

WO 2014/117000 A2 relates to a water purification component according to the preamble of claim 1 of the present invention, which may be integrated in a medicament production plant and/or a blood treatment system, and removes chloramine and other chlorine compounds

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 3

deionizes water

Methodology Applied
Scientific EffectIon exchange: Ion Exchange

Data Source

PatentEP3560532B1Medicament preparation and treatment devices and systems
Publication Date: 2023.04.19 NXSTAGE MEDICAL INC
  • EP3560532B1 patent drawingFigure 1~2
  • EP3560532B1 patent drawingFigure 3A~4
  • EP3560532B1 patent drawingFigure 5

AI summary

A medicament preparation system, according to an embodiment, includes a water purification module and a medicament proportioning module. The system is configured to allow convenient and safe use in a home environment or a critical care environment as well as others affording safety, reliability, and a compact form factor.