Composite Bone Graft Device with Resorbable Mesh Casing
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Solution Overview
Problem
Current bone grafts for spinal fusion, whether synthetic or natural, often fail to provide adequate support and stability, leading to graft migration and insufficient bone growth, especially in degenerative disc disease and other spinal conditions, due to their granular form and limited durability.
Innovation Solution
A composite bone graft device combining allograft bone with a synthetic bone substitute, such as hydroxyapatite and gelatin, contained within a permeable pouch or mesh casing, which remains malleable during implantation and is designed to promote controlled resorption and bone regeneration, reducing graft migration and enhancing fusion stability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If granular or putty forms of bone void fillers are used, then the material is malleable during implantation, but graft migration occurs and the material cannot maintain shape
Solution Approach 1:
The patent uses a flexible membrane envelope containing the bone graft material. This membrane allows the material to be malleable during implantation while maintaining shape retention once implanted, directly resolving the contradiction between ease of operation and stability of composition.
2Reliability
If synthetic bone grafts are used, then the supply is unlimited and disease transmission risk is eliminated, but the grafts collapse and resorb too quickly
Solution Approach 1:
The patent combines synthetic bone graft material with a membrane envelope system. The synthetic material provides unlimited supply and disease transmission safety, while the membrane structure prevents collapse and extends durability, resolving the contradiction between reliability and duration of action.
3Reliability
If natural autologous bone grafts are used, then the material promotes good bone formation, but the supply is limited
Solution Approach 1:
The patent changes the parameters of synthetic bone graft material to match the beneficial properties of natural bone, creating a synthetic alternative that provides both unlimited supply and good bone formation promotion, resolving the contradiction between reliability and quantity of substance.
4Stability of the object's composition
If the bone graft material is contained in a pouch or bag, then graft migration is eliminated, but the device complexity increases
Solution Approach 1:
The patent employs a flexible membrane envelope that contains the bone graft material. This simple yet effective structure eliminates graft migration while adding minimal complexity to the device, resolving the contradiction between stability of composition and device complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composite bone graft effectively promotes solid fusion by maintaining the graft at the site of pathology, reducing migration, and facilitating controlled resorption and bone regeneration, leading to improved spinal fusion outcomes and longer-term stability.
Implementation Method 1
contained in a pouch or bag that is permeable
Data Source
AI summary
A composite bone graft which comprises an allograft bone component; a synthetic bone substitute, wherein the synthetic bone substitute is in contact with the allograft bone component. The composite is arranged within a resorbable mesh casing.