Composite Dressing with Embedded Fabric for Hemostasis
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Solution Overview
Problem
Conventional medical dressings for deep cavity wounds, puncture wounds, post-partum hemorrhage, and internal bleeding lack effective hemostasis and fluid absorbency, often relying on adhesives or stitching that are not suitable for in situ applications and can lose functionality when exposed to fluids, leading to longer surgeries and increased costs.
Innovation Solution
A composite dressing comprising a porous matrix made of biomaterials with a fabric support embedded within, eliminating the need for adhesives or stitching, and prepared through a method involving immersion in a biomaterial solution, freezing, and solvent removal to create a cohesive bond between layers, enhancing fluid absorption and mechanical strength.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If adhesives or stitching are used to bond multiple layers in composite dressings, then the layers are held together, but the adhesives lose functionality when exposed to fluids and the porous structure may collapse
Solution Approach 1:
The invention extracts and eliminates the adhesive component from the composite dressing system. Instead of using adhesives to bond the porous matrix to the backing layer, the patent employs a mechanical interlocking mechanism where the porous matrix is physically embedded into the backing layer structure, removing the harmful adhesive element that fails in fluid environments.
Solution Approach 2:
The invention applies nesting by embedding the porous matrix within the backing layer structure. The porous matrix is inserted into pockets or cavities formed in the backing layer, creating a nested configuration where one component (porous matrix) is housed within another (backing layer), providing secure bonding without adhesives.
2Strength
If swelling porous layers are bonded with adhesives or backing layers with different expansion proportions, then the layers are attached, but the layers detach or break apart when swelling occurs
Solution Approach 1:
The porous matrix is nested within the backing layer structure, allowing independent swelling of the porous layer while maintaining structural integrity through the nested configuration. The backing layer acts as a container that accommodates volume changes of the porous matrix during swelling without causing detachment.
Solution Approach 2:
The invention changes the bonding mechanism from chemical (adhesive bonding) to mechanical (physical embedding and interlocking). This parameter change in the bonding approach allows the structure to accommodate swelling-induced dimensional changes while maintaining attachment strength through friction and mechanical interlocking rather than chemical bonds.
3Quantity of substance
If conventional gauze dressings are used to absorb fluids and wall off surgical sites, then fluid absorption and site isolation are achieved, but hemostasis is not promoted leading to longer surgeries
Solution Approach 1:
The invention creates a composite dressing combining a porous hemostatic matrix with a supportive backing layer. The porous matrix is made from hemostatic materials (such as gelatin, chitosan, or collagen) that promote blood clotting, while the backing layer provides structural support. This composite structure simultaneously achieves fluid absorption and active hemostasis promotion, reducing surgery duration.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composite dressing achieves high fluid absorbency and maintains structural integrity when saturated, providing effective hemostasis and ease of application, with a strong bonding mechanism that resists separation, allowing for efficient control of bleeding and easy removal without residue.
Implementation Method 1
contacting the fabric substrate with a solution of the biomaterial; at least partially immersing the fabric substrate in the solution of the biomaterial
Implementation Method 2
immersing the fabric substrate in the solution of the biomaterial
Implementation Method 3
freezing the solution of the biomaterial comprising the immersed fabric substrate at a controlled rate
Implementation Method 4
freezing the solution of the biomaterial comprising the immersed fabric substrate at a controlled rate
Implementation Method 5
removing solvent from the frozen biomaterial solution
Implementation Method 6
removing solvent from the frozen biomaterial solution
Implementation Method 7
The adhesives, however, are generally not suitable for in situ applications... composite dressings which do not require adhesives, stitching or chemical crosslinking agents
Data Source
AI summary
The present disclosure provides a composite dressing comprising a combination of porous matrix and fabric substrate wherein at least one of said porous matrix and fabric substrate is composed biomaterial(s) and wherein the fabric substrate is at least partially embedded in the porous matrix. Further, the disclosure provides a method for preparation of said composite dressing, wherein said method enables production of the composite dressing having cohesive bonding between porous matrix and fabric support without use of any adhesive, stitching or chemical crosslinking agent between the two layers. The composite dressing exhibits high peel strength in both dry and wet conditions and has applications such as hemostatic dressings for deep cavity wounds, puncture wounds, post-partum hemorrhage and internal hemostatic agents.