Composite Implant with Dual Resorption Rates for Bone Ingrowth

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Solution Overview

Problem

Current orthopaedic implants made of non-resorbable materials can cause long-term complications and lack biocompatibility, as they do not degrade naturally with the body, whereas bioresorbable materials are limited by uniform degradation profiles that do not support bone ingrowth and mechanical strength retention effectively.

Innovation Solution

A composite material is developed comprising a first material with a specific resorption rate and a second material with a different resorption rate, forming a porous structure that allows for bone ingrowth and improved strength retention, where the first material is resorbed at a faster rate than the second, enabling gradual bone replacement and mechanical support.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If non-resorbable materials are used for orthopaedic implants, then mechanical strength and structural stability are maintained long-term, but long-term complications arise and biocompatibility is reduced due to lack of natural degradation

Engineering Contradiction:
Improvelong-term biocompatibilityVSAvoidlong-term degradation complications
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent applies parameter changes by modifying the chemical composition and molecular weight of the polymer material to control the degradation rate. By adjusting these parameters, the implant can maintain structural integrity during the healing period while gradually degrading to improve biocompatibility and eliminate long-term complications.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite materials by combining polymer matrices with ceramic particles or other bioactive materials. This composite structure provides both the mechanical strength needed for immediate post-operative stability and the controlled degradation characteristics for long-term biocompatibility, resolving the contradiction between durability and biocompatibility.

Inventive Principle:
Principle #40Composite materials

2Strength

If uniform resorbable materials are used, then complete degradation without residues is achieved, but bone ingrowth and mechanical strength retention are not effectively supported

Engineering Contradiction:
Improvemechanical strength retentionVSAvoiddegradation profile uniformity
Core Design Contradiction:
StrengthVSDevice complexity

Solution Approach 1:

The patent applies local quality by creating a non-uniform degradation profile where different regions of the implant degrade at different rates. The surface layer may degrade faster to promote bone ingrowth, while the core maintains structural integrity longer to provide mechanical support. This spatial variation in degradation quality resolves the contradiction between strength retention and bone ingrowth support.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent segments the implant structure into distinct zones with different degradation characteristics. By dividing the implant into regions with varying porosity, cross-linking density, or material composition, each segment can perform its specific function: some regions facilitate bone ingrowth while others maintain mechanical strength, eliminating the need for uniform degradation.

Inventive Principle:
Principle #1Segmentation

3Duration of action of stationary object

If faster resorption rate is used, then complete degradation occurs more quickly, but mechanical support is reduced during the healing period

Engineering Contradiction:
Improveresorption timeVSAvoidmechanical support duration
Core Design Contradiction:
Duration of action of stationary objectVSStrength

Solution Approach 1:

The patent applies dynamics by designing the implant with time-dependent mechanical properties. The material transitions from a rigid, load-bearing structure in the early post-operative period to a gradually softening structure that transfers load to healing bone. This dynamic adaptation allows fast resorption to occur while maintaining adequate mechanical support throughout the healing process.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent employs preliminary action by pre-establishing a gradient structure or pre-cross-linking patterns before implantation. This preliminary configuration ensures that as degradation begins, the mechanical properties evolve in a predictable manner that maintains support. The pre-designed structure allows rapid resorption to proceed without compromising the mechanical support needed during critical healing phases.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composite material allows for controlled bone ingrowth, improved strength retention, and enhanced biocompatibility by providing a gradual transition of load to newly regenerating tissue, reducing long-term degradation complications and ensuring complete resorption without leaving residues.

Implementation Method 1

a first material operable to be resorbed into an anatomy at a first resorption rate and defining a plurality of pores. A second material operable to be resorbed into the anatomy at a second resorption rate can be positioned relative to the first material to substantially fill at least a sub-plurality of the plurality of the pores.

Methodology Applied
Scientific EffectResorption: Decomposition (biological)

Data Source

PatentUS7879109B2Continuous phase composite for musculoskeletal repair
Publication Date: 2011.02.01 HIGHRIDGE MEDICAL LLC
  • US7879109B2 patent drawing
  • US7879109B2 patent drawing
  • US7879109B2 patent drawing

AI summary

A composite material for positioning in the anatomy to form a selected function therein. The composite may be resorbable over a selected period of time. The composite may allow for selected bone ingrowth as absorption of the composite occurs.