Composite Light Adjustable IOL Bonding for Surgical Stability

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Solution Overview

Problem

Existing intraocular lenses (IOLs) face challenges such as misalignment and uneven healing post-surgery, particularly with silicone-based light adjustable lenses, which unfold quickly during implantation, and acrylate-based lenses lacking light adjustability, leading to suboptimal surgical outcomes.

Innovation Solution

A composite light adjustable intraocular lens (CLA IOL) combining an acrylic intraocular insert with a silicone-based light adjustable lens and haptics, allowing for post-surgical adjustments to correct misalignments and provide optical corrections, featuring a modular design for improved surgical control and safety.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a silicone-based light adjustable lens is used, then light adjustability and optical correction capability are improved, but the lens unfolds quickly during implantation making surgical control difficult

Engineering Contradiction:

Improvelight adjustabilityVSAvoidsurgical control

Core Design Contradiction:

Adaptability or versatilityVSEase of operation

Solution Approach 1:

The IOL is divided into two separate components: a stable acrylic intraocular insert that provides structural support and surgical stability, and a silicone-based light adjustable lens that provides optical correction capability. This segmentation allows each component to fulfill its specific function optimally without compromising the other.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The silicone-based light adjustable lens is positioned to work in conjunction with the acrylic intraocular insert, where the acrylic insert serves as a stable base structure and the silicone lens provides the adjustable optical layer. This nested arrangement ensures the silicone lens remains controllable during surgery while maintaining its light-adjustable properties.

Inventive Principle:

Principle #7Nested doll (Nesting)

2Ease of operation

If an acrylic intraocular insert is used, then surgical control and stability during implantation are improved, but light adjustability and post-surgical optimization are lost

Engineering Contradiction:

Improvesurgical controlVSAvoidlight adjustability

Core Design Contradiction:

Ease of operationVSAdaptability or versatility

Solution Approach 1:

The invention merges two previously separate IOL technologies into a single composite device: the acrylic intraocular insert (providing surgical stability) and the silicone-based light adjustable lens (providing post-surgical adaptability). This combination allows the system to achieve both surgical control and light adjustability simultaneously.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The IOL system uses composite construction with an acrylic intraocular insert as the base material and a silicone-based light adjustable lens as the functional overlay. This composite approach leverages the advantageous properties of both materials: the stability and ease of handling of acrylic, and the light-adjustable optical properties of silicone.

Inventive Principle:

Principle #40Composite materials

3Adaptability or versatility

If existing light adjustable lenses are used, then post-surgical optical adjustments are possible, but attachment reliability and long-term stability are compromised

Engineering Contradiction:

Improvepost-surgical adjustmentVSAvoidattachment stability

Core Design Contradiction:

Adaptability or versatilityVSReliability

Solution Approach 1:

The acrylic intraocular insert acts as an intermediary component between the haptics and the silicone-based light adjustable lens. It provides a stable attachment surface that ensures reliable long-term positioning of the light adjustable lens while maintaining the post-surgical adjustment capability.

Inventive Principle:

Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The CLA IOL addresses misalignment issues by enabling precise post-surgical adjustments, improving surgical outcomes and reducing complications, while maintaining mechanical robustness and safety, thus enhancing the market acceptance of advanced IOLs.

Implementation Method 1

the light adjustable lens and the intraocular lens are chemically bonded together

Methodology Applied

Scientific EffectChemical bonding: Chemical Bonding

Implementation Method 2

a photopolymerizable composition, dispersed in the first polymer matrix; and a photoinitiator, configured to be activated upon absorbing a refraction modulating illumination; and to initiate the photopolymerization of the photopolymerizable composition

Methodology Applied

Scientific EffectPhotopolymerization: Photopolymerisation

Implementation Method 3

a photoinitiator, configured to be activated upon absorbing a refraction modulating illumination

Methodology Applied

Scientific EffectLight absorption: Absorption (EM radiation)

Data Source

PatentEP4135623B1Composite light adjustable intraocular lens with adhesion promoter

Publication Date: 2026.04.08 RXSIGHT INC

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AI summary

A composite light adjustable intraocular lens can include an acrylic intraocular insert; a silicone-based light adjustable lens, attached to the acrylic intraocular insert with an adhesion promoter; and haptics; wherein the adhesion promoter includes a first orthogonal functional group, configured to bond with an acrylic component of the acrylic intraocular insert; and a second orthogonal functional group, configured to bond with a silicone component of the silicone-based light adjustable lens.