Composite Light Source for Non-Invasive Blood Glucose Detection
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Solution Overview
Problem
Current non-invasive detection instruments for blood glucose concentration face challenges in achieving high sensitivity and accuracy due to overlapping absorption wavelength ranges and insufficient energy in continuous light sources, leading to weakened signal-to-noise ratio (SNR) and reduced accuracy.
Innovation Solution
A composite light source system combining a continuous light source with one or several discrete light sources, such as laser diodes (LDs), is used to enhance NIR light intensity and spectral measurement across multiple wavelengths, improving the SNR and accuracy of blood glucose detection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If a continuous light source is used for NIR spectral measurement, then the spectral coverage is broad, but the energy at specific wavelengths is insufficient leading to low SNR
Solution Approach 1:
The patent combines a continuous light source (halogen lamp) with multiple discrete light sources (laser diodes at 1450nm, 1550nm, and LED at 1650nm) to form a composite light source. This merging allows the system to achieve both broad spectral coverage from the continuous source and high energy concentration at specific wavelengths from the discrete sources, resolving the contradiction between spectral versatility and energy intensity.
2Measurement precision
If multiple discrete light sources are used to cover multiple wavelengths, then the measurement precision improves, but the device complexity increases
Solution Approach 1:
The patent employs a composite light source system where different light sources (laser diodes and LED) operate at different wavelengths but serve the same function of providing high-intensity illumination for spectral measurement. This multi-functionality approach allows the system to achieve high measurement precision across multiple wavelengths while managing device complexity through standardized optical components and integrated control.
3Measurement precision
If the NIR light intensity is increased to improve SNR, then the detection accuracy improves, but the available light sources with sufficient energy are limited
Solution Approach 1:
The patent creates a composite light source system combining different types of light sources (laser diodes and LED) with complementary spectral characteristics. This composite approach enables the system to achieve high NIR light intensity across multiple wavelength regions by leveraging the strengths of each light source type, thereby improving detection accuracy without being constrained by the limitations of any single light source.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composite light source system enables comprehensive and accurate detection of blood glucose concentration by increasing spectral measurement points and enhancing NIR light intensity, thereby improving the overall accuracy and stability of the detection system.
Implementation Method 1
because different components within a substance especially human tissue possess different light absorption coefficients in NIR range
Data Source
AI summary
The present invention discloses a spectral measurement method via continuous light source and discrete light source, and a measurement instrument for non-invasive detection of human body tissue components. Said instrument includes an incident unit, a probe, a receiving unit and a data processing unit. Said composite spectral measurement method improves or strengthens the output light intensity at the wavelength that carries information of the target component within human body. It enables the spectral detection in the whole wavelength range, and thus significantly enhances the SNR of the detecting system. In the non-invasive detection instrument, light from both the continuous light source and discrete light source can be firstly selectively light-split by AOTF, or AOTF conducts light-splitting for the continuous light source, while the discrete light source LD is controlled by a spatial chopper. When data of the spectral curves achieved from said continuous light source and discrete light source are processed, data acquired under different measuring modes can be compared.