Composite Animal Litter with Chromogenic Indicator for Disease Detection

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Solution Overview

Problem

Current methods for detecting feline urinary tract disease in animal litter face challenges such as instability under varying conditions, insufficient visibility of color changes, offensive odors, and poor shelf-life stability, making them inconvenient and ineffective for pet owners.

Innovation Solution

A composite litter material comprising an absorptive polymer matrix with exfoliated clay and a chromogenic indicator, along with an oxidizing agent, which activates upon contact with peroxidase or pseudoperoxidase activity in urine to provide a visible color change for detection, is developed. This material is stable, odor-free, and retains its effectiveness for a sufficient duration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If diagnostic agents are incorporated into animal litter for detection purposes, then early detection capability is improved, but stability under varying conditions deteriorates

Engineering Contradiction:
Improveearly detection capabilityVSAvoidstability under varying conditions
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The detection system is segmented into discrete particles distributed throughout the litter, with each particle containing its own complete detection chemistry (chromogen, peroxide, buffer, thickener). This segmentation isolates the reactive components within individual stable units that resist degradation under varying environmental conditions while maintaining detection capability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention uses composite particles combining multiple materials with complementary properties: chromogenic indicators for color change, organic peroxides for oxidation stability, buffers for pH control, and thickeners for fluid management. This composite structure ensures stable performance across varying conditions while enabling reliable disease detection.

Inventive Principle:
Principle #40Composite materials

2Ease of operation

If detection reagents are mixed with animal litter, then convenience for pet owners is improved, but visibility of color changes deteriorates

Engineering Contradiction:
Improveconvenience for pet ownersVSAvoidvisibility of color changes
Core Design Contradiction:
Ease of operationVSLoss of information

Solution Approach 1:

The detection particles are designed with local quality enhancements: bright chromogenic indicators concentrated within each particle create intense localized color changes that stand out against the litter background. The particles themselves are sized and shaped to maximize visibility when they change color upon detecting blood in urine.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The invention employs chromogenic indicators that produce distinct, vivid color changes when activated by peroxidase activity in blood-containing urine. These color changes are engineered to be highly visible against the litter material, ensuring that pet owners can easily detect the diagnostic signal without missing subtle cues.

Inventive Principle:
Principle #32Color changes

3Reliability

If diagnostic beads are used for detection, then detection function is improved, but offensive odors are generated

Engineering Contradiction:
Improvedetection functionVSAvoidoffensive odors
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The invention extracts and eliminates odor-causing components from the detection system. The detection particles are formulated without materials that generate offensive odors during storage or use, while maintaining all necessary detection functions. This extraction of harmful olfactory properties allows the litter to perform diagnostic detection without creating unpleasant smells for pet owners.

Inventive Principle:
Principle #2Taking out (Extraction)

4Ease of manufacture

If detection composition is coated on surface of particulate material, then ease of manufacture is improved, but shelf-life stability deteriorates

Engineering Contradiction:
Improveease of manufactureVSAvoidshelf-life stability
Core Design Contradiction:
Ease of manufactureVSDuration of action of stationary object

Solution Approach 1:

The invention merges all detection composition components (chromogen, peroxide, buffer, thickener) directly into the particulate material itself during manufacturing, creating a homogeneous integrated particle structure. This merging eliminates the separate coating step while enhancing shelf-life stability by ensuring uniform distribution and protection of all reactive components throughout the particle matrix, preventing degradation that would occur with surface-only coating.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composite material effectively detects feline urinary tract disease with a stable and visible color change, remaining effective for at least 6 hours after exposure, and is convenient and reliable for pet owners to use, while avoiding the drawbacks of existing technologies.

Implementation Method 1

an oxidizing agent distributed and stabilized within the solid matrix such that the oxidizing agent is available and responsive to peroxidase or pseudoperoxidase activity in the urine to activate the chromogenic indicator

Methodology Applied
Scientific EffectOxidation: Oxidation

Data Source

PatentEP2433127B1Composite animal litter material and methods
Publication Date: 2014.04.02 7905122 CANADA
  • EP2433127B1 patent drawingFigure 1
  • EP2433127B1 patent drawingFigure 2
  • EP2433127B1 patent drawingFigure 3

AI summary

A composite litter material for detecting a disease, such as urinary tract disease, when contacted by feline urine includes an absorptive polymer material forming a solid matrix, exfoliated clay embedded and dispersed within the solid matrix, a chromogenic indicator provided within the solid matrix, and an oxidizing agent distributed and stabilized within the solid matrix to be responsive to peroxidase activity in the urine to activate the chromogenic indicator. A method for detecting or diagnosing a feline disease includes contacting urine with the material and detecting a color change. A method of manufacturing the composite material includes preparing a mixture comprising the absorptive polymer and water and distributing the exfoliated clay, chromogenic indicator and oxidizing agent within the mixture, preferably by extrusion and addition of the components at particular points in processing the polymer mixture.