Compound Swab System for Efficient Pool Testing Specimen Collection

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Solution Overview

Problem

Current specimen collection techniques for pool testing face challenges such as dilution effects in high-sensitivity tests and the need for repeated swabbing, particularly in reverse transcription polymerase chain reaction (RT-PCR) tests, which can be inefficient and resource-intensive.

Innovation Solution

A compound swab system featuring a first swab for pool testing and a second swab for separate testing based on pool test results, along with a container and receptacle design for efficient separation and storage of swabs, and a suction-enhanced swab for improved specimen capture.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional swabbing is used for pool testing, then specimen collection can be performed, but repeated collection is needed which reduces efficiency and increases resource consumption

Engineering Contradiction:
Improvespecimen collection efficiencyVSAvoidtime for repeated collection
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent combines multiple swabs (e.g., two or more) into a single compound swab assembly that can collect specimens from multiple subjects simultaneously during one insertion action. This merging approach eliminates the need for repeated separate swabbing operations, thereby improving collection efficiency and reducing time loss.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The compound swab is designed to perform multiple functions: it can collect specimens from multiple subjects in parallel, and the swabs can be separated afterward for different testing purposes (pool testing or individual testing). This multi-functionality allows a single device to replace multiple separate swabbing operations.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Quantity of substance

If specimens are collected for pool testing, then resource consumption is reduced, but dilution effects occur which compromise test sensitivity

Engineering Contradiction:
Improvenumber of specimens testedVSAvoidtest sensitivity
Core Design Contradiction:
Quantity of substanceVSMeasurement precision

Solution Approach 1:

The compound swab contains multiple separate swabs that are collected together but remain individually separable. This segmentation allows the specimen to be divided into separate portions for different testing strategies - some for pool testing to reduce overall resource consumption, and others available for individual testing to maintain sensitivity when needed.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention changes the parameter of specimen volume per swab by using multiple swabs with smaller individual collection volumes. This approach maintains adequate concentration for sensitive tests while still enabling pool testing benefits, as the total specimen amount is distributed across multiple smaller collections rather than one large dilution.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If multiple separate swabs are used for pool testing, then more swabs are consumed, but specimen collection from multiple subjects is more efficient

Engineering Contradiction:
Improvebatch specimen collection capabilityVSAvoidnumber of swabs used
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

Multiple swabs are merged into a single compound swab assembly that can be inserted into a single subject's nasal passage simultaneously. This reduces the number of insertions needed while still collecting from multiple subjects' specimens in one action, and the swabs can be separated afterward for appropriate allocation to pool or individual testing.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The compound swab assembly serves multiple purposes: it enables efficient batch collection from multiple subjects in one insertion, provides separable individual swabs for flexible testing strategies, and reduces overall swab consumption by consolidating multiple collection functions into a single device that can be reused or appropriately allocated.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compound swab system reduces testing requirements, conserves resources, and enhances specimen collection efficiency, facilitating effective pool testing on a large scale by allowing separate analysis of specimens and reducing the number of swabs needed.

Implementation Method 1

a suction enhancer in fluid communication with the channel, the suction enhancer activatable to establish a flow of fluid through the channel in a first direction from the second end toward the first end thereby establishing suction at the second end of the shaft through the collection tip

Methodology Applied
Scientific EffectSuction: Suction

Data Source

PatentEP4175599B1Specimen collection and storage for pool testing and similar
Publication Date: 2024.10.30 FRESENIUS MEDICAL CARE HOLDINGS INC
  • EP4175599B1 patent drawingFigure 1~3
  • EP4175599B1 patent drawingFigure 4~5
  • EP4175599B1 patent drawingFigure 6

AI summary

The present teachings generally include devices, systems, kits, and methods for collecting, storing, and transporting specimens, e.g., in the context of pool testing. For example, the present teachings may include a compound swab featuring a first swab and a second swab, where the first swab can be detached for pool testing and the second swab can be preserved for testing based on results of the pool test. The present teachings may also or instead include a container having a separator structurally configured to separate swabs of a compound swab. Further, the present teachings may include a swab having a suction enhancer to promote the capture of a specimen on a collection tip thereof. The present teachings may also or instead include a receptacle that can house a plurality of swabs and sever at least a portion of the collections tips thereof, e.g., for pool testing.