Compounded Footbath Solution for Bacterial and Fungal Infections

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Solution Overview

Problem

There is a need for compositions and methods that efficiently treat or prevent the progression and reoccurrence of bacterial infections and/or fungal infections that affect at least part of one or both feet, as existing treatments are inadequate in addressing the complexity of foot infections.

Innovation Solution

A compounded composition is disclosed, which includes combining a diluent with clindamycin or erythromycin solutions to form a footbath solution. This solution is topically administered to the affected skin area of the foot, either by submerging the foot in a footbath container or through direct application, to treat or prevent bacterial or fungal infections.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing treatments are used for foot infections, then treatment simplicity is maintained, but treatment effectiveness is inadequate

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidtreatment complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple anti-infective agents (antibacterial and antifungal) into a single compounded topical composition. This merging of multiple therapeutic functions into one formulation addresses the inadequacy of existing single-agent treatments while maintaining ease of application as a single topical product.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention uses composite pharmaceutical formulations containing multiple active ingredients with different mechanisms of action. The compounded composition integrates antibacterial agents (e.g., bacitracin, neomycin) and antifungal agents (e.g., clotrimazole, miconazole) into a unified topical preparation, providing broad-spectrum coverage for complex foot infections.

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If multiple anti-infective agents are combined in one composition, then broad-spectrum coverage is achieved, but formulation complexity increases

Engineering Contradiction:
Improvebroad-spectrum coverageVSAvoidformulation complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The compounded topical composition is designed to perform multiple functions simultaneously: antibacterial protection, antifungal protection, and anti-inflammatory action. This multi-functional formulation provides universal coverage for various types of foot infections (bacterial, fungal, or mixed) without requiring separate treatments for each condition.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

Multiple pharmacologically distinct agents are merged into a single topical formulation. The composition integrates antibacterial components, antifungal components, and anti-inflammatory components into one cohesive product, achieving broad-spectrum coverage while simplifying the treatment regimen to a single application.

Inventive Principle:
Principle #5Merging (Combining)

3Ease of operation

If topical footbath solution is administered, then ease of application is improved, but treatment precision may be reduced

Engineering Contradiction:
Improveease of applicationVSAvoidtreatment precision
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The treatment approach segments the application process into a practical footbath format, allowing the compounded solution to be applied to the entire affected area simultaneously. This segmentation of the treatment area into a manageable footbath application maintains ease of use while ensuring comprehensive coverage of all infected regions.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS12268701B2Compositions and methods for treating an infection
Publication Date: 2025.04.08 CMPD LICENSING LLC
  • US12268701B2 patent drawing
  • US12268701B2 patent drawing
  • US12268701B2 patent drawing

AI summary

A method of treating or preventing one or both of a bacterial infection or fungal infection of a foot of a subject includes combining a diluent and at least one of a clindamycin solution or an erythromycin solution to form a footbath solution. The method may further include topically administering the footbath solution to the subject. Administering may include contacting with the footbath solution a skin area of the foot of the subject that is infected or suspected to be infected.