Compressible Mesh Occlusion Device for Aneurysm Flow Disruption
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current occlusion devices are inadequate for treating large and irregularly shaped aneurysms, particularly neurovascular aneurysms, as they fail to achieve sufficient flow disruption and compartmentalization, leading to incomplete occlusion and potential rupture risks.
Innovation Solution
A compressible mesh-based occlusion device with axial mesh carriages and discreet pinch points, designed to expand and fill the aneurysm sac, providing a 3-dimensional network for flow disruption and thrombus formation, suitable for larger and more complex aneurysm shapes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional occlusion devices are used, then the treatment is simple and easy to deliver, but they fail to achieve sufficient flow disruption and compartmentalization for large and irregularly shaped aneurysms
Solution Approach 1:
The occlusion device is divided into multiple compressible mesh carriages that can be independently deployed within the aneurysm sac. Each carriage creates localized flow disruption and compartmentalization, allowing the device to effectively occlude large and irregularly shaped aneurysms while maintaining a deliverable form through the catheter.
2Ease of operation
If the device is made compact for delivery, then it can be safely delivered through catheters, but it must expand to a larger size to achieve sufficient flow disruption and fill the aneurysm sac
Solution Approach 1:
The mesh carriages are designed to be dynamically changeable in volume, transitioning from a compressed low-profile state during delivery through the catheter to an expanded state upon deployment within the aneurysm sac. This dynamic transformation allows the device to meet both deliverability requirements and therapeutic effectiveness requirements.
3Reliability
If the device expands to fill large aneurysms, then flow disruption and stasis are achieved, but the device must be large enough to accommodate various aneurysm sizes and shapes
Solution Approach 1:
The device consists of multiple modular mesh carriages that can be selectively deployed to match the size and shape of the aneurysm sac. This segmentation allows the device to adapt to varying aneurysm dimensions while collectively achieving sufficient flow disruption and stasis when fully expanded.
Solution Approach 2:
The compressible mesh carriage design provides universal applicability across different aneurysm sizes and shapes. The same basic carriage structure can be expanded to different volumes and configured to fit various geometries, making the device versatile for treating a wide range of aneurysm presentations.
Data Source
AI summary
Provided herein is an occlusion device for implantation into a body lumen or aneurysm comprising, a continuous compressible mesh structure comprising axial mesh carriages configured end to end, wherein each end of each carriage is a pinch point in the continuous mesh structure. Also provided herein is a kit comprising the occlusion device disclosed herein and a means for delivery thereof. Methods of manufacture and use of the occlusion device are also disclosed.