Computational Lightfield Ophthalmoscope for Integrated Eye Imaging

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Solution Overview

Problem

There is a global shortage of eye care professionals capable of conducting comprehensive eye exams, which are costly and require sophisticated equipment and extensive training, limiting access to vision correction and ocular disease screening.

Innovation Solution

A computational lightfield ophthalmoscope device that uses computational optics to simultaneously characterize aberrations and capture high-resolution images of the anterior and posterior segments of the eye, utilizing a diffuser and a single plenoptic camera, with optional neural networks for automated pathology detection, reducing the need for multiple expensive systems and trained providers.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If multiple expensive ophthalmic systems are used to conduct comprehensive eye exams, then measurement precision and diagnostic capability are improved, but device complexity and cost increase

Engineering Contradiction:
Improveaberration measurement precisionVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple ophthalmic measurement functions (aberration measurement, anterior segment imaging, posterior segment imaging) into a single integrated device. The system uses a unified optical path with beam splitters to direct different wavelengths of light to different eye segments, eliminating the need for multiple separate expensive systems while maintaining comprehensive diagnostic capability

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The ophthalmoscope is designed as a multi-functional device that can simultaneously perform aberration measurement, anterior segment imaging, and posterior segment imaging. The single device incorporates multiple light sources for different wavelengths, beam splitters for routing light paths, and imaging capabilities for both eye segments, making one device replace multiple specialized instruments

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If sophisticated equipment and extensive training are required for eye exams, then diagnostic accuracy is improved, but ease of operation and accessibility worsen

Engineering Contradiction:
Improveocular disease screening accuracyVSAvoidoperational simplicity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The device incorporates automated processing capabilities where the captured light field images are computationally processed to automatically generate aberration measurements and diagnostic information. The system performs self-calibration and automated analysis, reducing the need for operator expertise while maintaining diagnostic accuracy

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces complex manual adjustment mechanisms with computational methods. Instead of requiring operators to manually align and focus multiple imaging systems, the device uses computational light field processing and digital refocusing algorithms to automatically achieve accurate measurements and images

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If multiple specialized imaging systems are deployed, then imaging quality is improved, but loss of time and operational efficiency worsen

Engineering Contradiction:
Improveimaging resolutionVSAvoidexamination time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The device performs multiple imaging functions continuously in a single operational sequence. The light field imaging captures data from both anterior and posterior segments simultaneously, and the computational processing generates all required measurements and images from a single set of captured photons, eliminating the need for repeated positioning and imaging sessions

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables affordable, accurate, and simplified eye exams that provide precise eyeglass prescriptions and ocular disease screening, while also allowing for assessment of brain-related conditions and health metrics, without the need for complex equipment or trained personnel.

Implementation Method 1

a diffuser positioned to receive light reflected by the fourth beam splitter, and configured to provide a pattern based on the light reflected by the fourth beam splitter

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 2

a fourth beam splitter arranged to reflect light remitted from the patient's eye

Methodology Applied
Scientific EffectReflection: Reflection

Data Source

PatentEP3817642B1Computational lightfield ophthalmoscope
Publication Date: 2025.09.17 JOHNS HOPKINS UNIVERSITY
  • EP3817642B1 patent drawingFigure 1A
  • EP3817642B1 patent drawingFigure 1B
  • EP3817642B1 patent drawingFigure 1C

AI summary

A device for ocular diagnostics may include one or more light sources configured to illuminate an anterior segment of a patient's eye, a diffuser positioned to receive light remitted from the anterior segment of the patient's eye, and configured to provide a pattern based on the light remitted, and an image sensor configured to obtain one or more images of the pattern to enable determination of one or more properties of the patient's eye.